mRNA regions where 80S ribosomes pause during translation elongation in vivo interact with protein uS19, a component of the decoding site

In eukaryotic ribosomes, the conserved protein uS19, formerly known as S15, extends with its C-terminal tail to the decoding site. The cross-linking of uS19 to the A site codon has been detected using synthetic mRNAs bearing 4-thiouridine (s(4)U) residues. Here, we showed that the A-site tRNA preven...

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Detalles Bibliográficos
Autores principales: Babaylova, Elena S, Gopanenko, Alexander V, Bulygin, Konstantin N, Tupikin, Alexey E, Kabilov, Marsel R, Malygin, Alexey A, Karpova, Galina G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954443/
https://www.ncbi.nlm.nih.gov/pubmed/31802126
http://dx.doi.org/10.1093/nar/gkz1145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954443/
https://www.ncbi.nlm.nih.gov/pubmed/31802126
http://dx.doi.org/10.1093/nar/gkz1145

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