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Polygenic approaches to detect gene–environment interactions when external information is unavailable

The exploration of ‘gene–environment interactions’ (G × E) is important for disease prediction and prevention. The scientific community usually uses external information to construct a genetic risk score (GRS), and then tests the interaction between this GRS and an environmental factor (E). However,...

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Detalles Bibliográficos
Autores principales:	Lin, Wan-Yu, Huang, Ching-Chieh, Liu, Yu-Li, Tsai, Shih-Jen, Kuo, Po-Hsiu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954453/ https://www.ncbi.nlm.nih.gov/pubmed/30219835 http://dx.doi.org/10.1093/bib/bby086

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