Restoration of Autophagic Flux Rescues Oxidative Damage and Mitochondrial Dysfunction to Protect against Intervertebral Disc Degeneration

Oxidative stress-induced mitochondrial dysfunction and nucleus pulposus (NP) cell apoptosis play crucial roles in the development of intervertebral disc degeneration (IDD). Increasing studies have shown that interventions targeting impaired autophagic flux can maintain cellular homeostasis by reliev...

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Detalles Bibliográficos
Autores principales: Kang, Liang, Xiang, Qian, Zhan, Shengfeng, Song, Yu, Wang, Kun, Zhao, Kangcheng, Li, Shuai, Shao, Zengwu, Yang, Cao, Zhang, Yukun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954474/
https://www.ncbi.nlm.nih.gov/pubmed/31976028
http://dx.doi.org/10.1155/2019/7810320

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