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Debranching thoracic endovascular aortic repair for distal aortic arch aneurysm in elderly patients aged over 75 years old

BACKGROUND: We examined the outcome of debranching thoracic endovascular aortic repair (d-TEVAR) without sternotomy for distal aortic arch aneurysm in patients aged ≥75 years. METHODS: Patients who underwent d-TEVAR or TAR for aortic arch aneurysm between 2008 and 2015 at our hospital and aged ≥75 y...

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Autores principales: Shiraya, Suguru, Nakamura, Yoshinobu, Harada, Shingo, Kishimoto, Yuichiro, Onohara, Takeshi, Otsuki, Yuki, Kurashiki, Tomohiro, Horie, Hiromu, Nishimura, Motonobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954511/
https://www.ncbi.nlm.nih.gov/pubmed/31924243
http://dx.doi.org/10.1186/s13019-020-1047-z
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author Shiraya, Suguru
Nakamura, Yoshinobu
Harada, Shingo
Kishimoto, Yuichiro
Onohara, Takeshi
Otsuki, Yuki
Kurashiki, Tomohiro
Horie, Hiromu
Nishimura, Motonobu
author_facet Shiraya, Suguru
Nakamura, Yoshinobu
Harada, Shingo
Kishimoto, Yuichiro
Onohara, Takeshi
Otsuki, Yuki
Kurashiki, Tomohiro
Horie, Hiromu
Nishimura, Motonobu
author_sort Shiraya, Suguru
collection PubMed
description BACKGROUND: We examined the outcome of debranching thoracic endovascular aortic repair (d-TEVAR) without sternotomy for distal aortic arch aneurysm in patients aged ≥75 years. METHODS: Patients who underwent d-TEVAR or TAR for aortic arch aneurysm between 2008 and 2015 at our hospital and aged ≥75 years were included. Age, sex, left ventricular ejection fraction, preoperative creatinine level, diabetes, cerebrovascular disease, and chronic obstructive pulmonary disease were matched using PS. RESULTS: Among 74 patients (d-TEVAR: 51, TAR: 23), 17 patients in each group were matched. No difference in surgical outcome was detected between the d-TEVAR and TAR groups, including 30-day death (0% vs. 0%), hospital death (5.8% vs. 0%: p = 0.31) and incidence of cerebral infarction (5.8% vs. 7.6%: p = 0.27) as well as the long-term outcomes of 5-year survival (92.8% vs. 74.8%: p = 0.30) and 5-year aorta-related event-free rate (88.2% vs. 100%: p = 0.15). Average duration of ICU stay (1.3 ± 1.1 days vs. 5.6 ± 1.3 days: p = 0.025) and hospital stay (16.5 ± 5.2 days vs. 37.7 ± 19.6 days: p = 0.017) were significantly shorter in the d-TEVAR group. CONCLUSION: Our results indicated that d-TEVAR is less invasive without affecting long-term outcome up to 5 years. Although the number of the patients included in the study was small, debranching TEVAR could be one of the treatments of the choice in the elderly, especially with comorbidities.
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spelling pubmed-69545112020-01-14 Debranching thoracic endovascular aortic repair for distal aortic arch aneurysm in elderly patients aged over 75 years old Shiraya, Suguru Nakamura, Yoshinobu Harada, Shingo Kishimoto, Yuichiro Onohara, Takeshi Otsuki, Yuki Kurashiki, Tomohiro Horie, Hiromu Nishimura, Motonobu J Cardiothorac Surg Research Article BACKGROUND: We examined the outcome of debranching thoracic endovascular aortic repair (d-TEVAR) without sternotomy for distal aortic arch aneurysm in patients aged ≥75 years. METHODS: Patients who underwent d-TEVAR or TAR for aortic arch aneurysm between 2008 and 2015 at our hospital and aged ≥75 years were included. Age, sex, left ventricular ejection fraction, preoperative creatinine level, diabetes, cerebrovascular disease, and chronic obstructive pulmonary disease were matched using PS. RESULTS: Among 74 patients (d-TEVAR: 51, TAR: 23), 17 patients in each group were matched. No difference in surgical outcome was detected between the d-TEVAR and TAR groups, including 30-day death (0% vs. 0%), hospital death (5.8% vs. 0%: p = 0.31) and incidence of cerebral infarction (5.8% vs. 7.6%: p = 0.27) as well as the long-term outcomes of 5-year survival (92.8% vs. 74.8%: p = 0.30) and 5-year aorta-related event-free rate (88.2% vs. 100%: p = 0.15). Average duration of ICU stay (1.3 ± 1.1 days vs. 5.6 ± 1.3 days: p = 0.025) and hospital stay (16.5 ± 5.2 days vs. 37.7 ± 19.6 days: p = 0.017) were significantly shorter in the d-TEVAR group. CONCLUSION: Our results indicated that d-TEVAR is less invasive without affecting long-term outcome up to 5 years. Although the number of the patients included in the study was small, debranching TEVAR could be one of the treatments of the choice in the elderly, especially with comorbidities. BioMed Central 2020-01-10 /pmc/articles/PMC6954511/ /pubmed/31924243 http://dx.doi.org/10.1186/s13019-020-1047-z Text en © The Author(s). 2020 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Shiraya, Suguru
Nakamura, Yoshinobu
Harada, Shingo
Kishimoto, Yuichiro
Onohara, Takeshi
Otsuki, Yuki
Kurashiki, Tomohiro
Horie, Hiromu
Nishimura, Motonobu
Debranching thoracic endovascular aortic repair for distal aortic arch aneurysm in elderly patients aged over 75 years old
title Debranching thoracic endovascular aortic repair for distal aortic arch aneurysm in elderly patients aged over 75 years old
title_full Debranching thoracic endovascular aortic repair for distal aortic arch aneurysm in elderly patients aged over 75 years old
title_fullStr Debranching thoracic endovascular aortic repair for distal aortic arch aneurysm in elderly patients aged over 75 years old
title_full_unstemmed Debranching thoracic endovascular aortic repair for distal aortic arch aneurysm in elderly patients aged over 75 years old
title_short Debranching thoracic endovascular aortic repair for distal aortic arch aneurysm in elderly patients aged over 75 years old
title_sort debranching thoracic endovascular aortic repair for distal aortic arch aneurysm in elderly patients aged over 75 years old
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954511/
https://www.ncbi.nlm.nih.gov/pubmed/31924243
http://dx.doi.org/10.1186/s13019-020-1047-z
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