Transcriptome analysis defines myocardium gene signatures in children with ToF and ASD and reveals disease-specific molecular reprogramming in response to surgery with cardiopulmonary bypass

BACKGROUND: Tetralogy of Fallot (ToF) and Atrial Septal Defects (ASD) are the most common types of congenital heart diseases and a major cause of childhood morbidity and mortality. Cardiopulmonary bypass (CPB) is used during corrective cardiac surgery to support circulation and heart stabilization....

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Detalles Bibliográficos
Autores principales: Raggi, Federica, Cangelosi, Davide, Becherini, Pamela, Blengio, Fabiola, Morini, Martina, Acquaviva, Massimo, Belli, Maria Luisa, Panizzon, Giuseppe, Cervo, Giuseppe, Varesio, Luigi, Eva, Alessandra, Bosco, Maria Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954611/
https://www.ncbi.nlm.nih.gov/pubmed/31924244
http://dx.doi.org/10.1186/s12967-020-02210-5

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