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Over-expression of CDX2 alleviates breast cancer by up-regulating microRNA let-7b and inhibiting COL11A1 expression

BACKGROUND: microRNA Let-7 serves as a tumor suppressor by targeting various oncogenic pathways in cancer cells. However, the underlying mechanism of its involvement in breast cancer remains largely unknown. With our research, our endeavor is to explore the role of the CDX2/let-7b/COL11A1 axis in br...

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Detalles Bibliográficos
Autores principales: Wang, Hongbin, Ren, Yanlv, Qian, Cheng, Liu, Jiaxin, Li, Ge, Li, Zhigao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954621/
https://www.ncbi.nlm.nih.gov/pubmed/31938021
http://dx.doi.org/10.1186/s12935-019-1066-9