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Goats naturally devoid of PrP(C) are resistant to scrapie

Prion diseases are progressive and fatal, neurodegenerative disorders described in humans and animals. According to the “protein-only” hypothesis, the normal host-encoded prion protein (PrP(C)) is converted into a pathological and infectious form (PrP(Sc)) in these diseases. Transgenic knockout mode...

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Detalles Bibliográficos
Autores principales:	Salvesen, Øyvind, Espenes, Arild, Reiten, Malin R., Vuong, Tram T., Malachin, Giulia, Tran, Linh, Andréoletti, Olivier, Olsaker, Ingrid, Benestad, Sylvie L., Tranulis, Michael A., Ersdal, Cecilie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954626/ https://www.ncbi.nlm.nih.gov/pubmed/31924264 http://dx.doi.org/10.1186/s13567-019-0731-2

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