HHV-8-negative multicentric Castleman disease presenting as a crescentic immune complexes membranoproliferative glomerulonephritis

Multicentric Castleman disease is a rare polyclonal lymphoproliferative disorder mainly associated with two renal manifestations: thrombotic microangiopathy and amyloidosis. Nevertheless, we report here a case of human herpes virus-8 negative multicentric Castleman disease with membranous proliferat...

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Autores principales: Nunes, Maria Brito, Rotman, Samuel, Duss, Francois-Regis, Halfon, Matthieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Rare Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954780/
https://www.ncbi.nlm.nih.gov/pubmed/31911409
http://dx.doi.org/10.1136/bcr-2019-231844
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author Nunes, Maria Brito
Rotman, Samuel
Duss, Francois-Regis
Halfon, Matthieu
author_facet Nunes, Maria Brito
Rotman, Samuel
Duss, Francois-Regis
Halfon, Matthieu
author_sort Nunes, Maria Brito
collection PubMed
description Multicentric Castleman disease is a rare polyclonal lymphoproliferative disorder mainly associated with two renal manifestations: thrombotic microangiopathy and amyloidosis. Nevertheless, we report here a case of human herpes virus-8 negative multicentric Castleman disease with membranous proliferative glomerulonephritis and extracapillary proliferation. A patient was successfully treated with corticosteroids, anti-CD20 and cyclophosphamide therapy.
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spelling pubmed-69547802020-01-23 HHV-8-negative multicentric Castleman disease presenting as a crescentic immune complexes membranoproliferative glomerulonephritis Nunes, Maria Brito Rotman, Samuel Duss, Francois-Regis Halfon, Matthieu BMJ Case Rep Rare Disease Multicentric Castleman disease is a rare polyclonal lymphoproliferative disorder mainly associated with two renal manifestations: thrombotic microangiopathy and amyloidosis. Nevertheless, we report here a case of human herpes virus-8 negative multicentric Castleman disease with membranous proliferative glomerulonephritis and extracapillary proliferation. A patient was successfully treated with corticosteroids, anti-CD20 and cyclophosphamide therapy. BMJ Publishing Group 2020-01-06 /pmc/articles/PMC6954780/ /pubmed/31911409 http://dx.doi.org/10.1136/bcr-2019-231844 Text en © BMJ Publishing Group Limited 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Rare Disease
Nunes, Maria Brito
Rotman, Samuel
Duss, Francois-Regis
Halfon, Matthieu
HHV-8-negative multicentric Castleman disease presenting as a crescentic immune complexes membranoproliferative glomerulonephritis
title HHV-8-negative multicentric Castleman disease presenting as a crescentic immune complexes membranoproliferative glomerulonephritis
title_full HHV-8-negative multicentric Castleman disease presenting as a crescentic immune complexes membranoproliferative glomerulonephritis
title_fullStr HHV-8-negative multicentric Castleman disease presenting as a crescentic immune complexes membranoproliferative glomerulonephritis
title_full_unstemmed HHV-8-negative multicentric Castleman disease presenting as a crescentic immune complexes membranoproliferative glomerulonephritis
title_short HHV-8-negative multicentric Castleman disease presenting as a crescentic immune complexes membranoproliferative glomerulonephritis
title_sort hhv-8-negative multicentric castleman disease presenting as a crescentic immune complexes membranoproliferative glomerulonephritis
topic Rare Disease
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954780/
https://www.ncbi.nlm.nih.gov/pubmed/31911409
http://dx.doi.org/10.1136/bcr-2019-231844
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