Protective effects of trimetazidine and coenzyme Q10 on cisplatin-induced cardiotoxicity by alleviating oxidative stress and mitochondrial dysfunction

OBJECTIVE: The objective of this study was to investigate the effects of trimetazidine (TMZ) and coenzyme Q10 (CoQ10) on cisplatin-induced cardiotoxicity in rat cardiomyocytes. METHODS: Rat cardiomyocytes were isolated and subjected to cisplatin (200 µM) treatment with and without TMZ (200 µM) and C...

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Detalles Bibliográficos
Autor principal: Zhao, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kare Publishing 2019
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955063/
https://www.ncbi.nlm.nih.gov/pubmed/31674935
http://dx.doi.org/10.14744/AnatolJCardiol.2019.83710

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955063/
https://www.ncbi.nlm.nih.gov/pubmed/31674935
http://dx.doi.org/10.14744/AnatolJCardiol.2019.83710

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