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Pancreatic head cancer: Open or minimally invasive pancreaticoduodenectomy?

Pancreatic head cancer still represents an insurmountable barrier for patients and pancreatic surgeons. Pancreaticoduodenectomy (PD) continues to be the operative standard of care and potentially curative procedure for pancreatic head cancer. Despite the rapid development of minimally invasive techn...

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Autores principales: Feng, Mengyu, Cao, Zhe, Sun, Zhiwei, Zhang, Taiping, Zhao, Yupei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955167/
https://www.ncbi.nlm.nih.gov/pubmed/31949389
http://dx.doi.org/10.21147/j.issn.1000-9604.2019.06.03
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author Feng, Mengyu
Cao, Zhe
Sun, Zhiwei
Zhang, Taiping
Zhao, Yupei
author_facet Feng, Mengyu
Cao, Zhe
Sun, Zhiwei
Zhang, Taiping
Zhao, Yupei
author_sort Feng, Mengyu
collection PubMed
description Pancreatic head cancer still represents an insurmountable barrier for patients and pancreatic surgeons. Pancreaticoduodenectomy (PD) continues to be the operative standard of care and potentially curative procedure for pancreatic head cancer. Despite the rapid development of minimally invasive techniques, whether the efficacy of minimally invasive pancreaticoduodenectomy (MIPD) is noninferior or superior to open pancreaticoduodenectomy (OPD) remains unclear. In this review, we summarized the history of OPD and MIPD and the latest staging and classification information for pancreatic head cancer as well as the proposed recommendations for MIPD indications for patients with pancreatic head cancer. By reviewing the MIPD- vs. OPD-related literature, we found that MIPD shows noninferiority or superiority to OPD in terms of safety, feasibility, enhanced recovery after surgery (ERAS) and several short-term and long-term outcomes. In addition, we analyzed and summarized the different MIPD outcomes in the USA, Europe and China. Certain debates over MIPD have continued, however, selection bias, the large number of low-volume centers, the steep MIPD learning curve, high conversion rate and administration of neoadjuvant therapy may limit the application of MIPD for pancreatic head cancer.
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spelling pubmed-69551672020-01-16 Pancreatic head cancer: Open or minimally invasive pancreaticoduodenectomy? Feng, Mengyu Cao, Zhe Sun, Zhiwei Zhang, Taiping Zhao, Yupei Chin J Cancer Res Review Article Pancreatic head cancer still represents an insurmountable barrier for patients and pancreatic surgeons. Pancreaticoduodenectomy (PD) continues to be the operative standard of care and potentially curative procedure for pancreatic head cancer. Despite the rapid development of minimally invasive techniques, whether the efficacy of minimally invasive pancreaticoduodenectomy (MIPD) is noninferior or superior to open pancreaticoduodenectomy (OPD) remains unclear. In this review, we summarized the history of OPD and MIPD and the latest staging and classification information for pancreatic head cancer as well as the proposed recommendations for MIPD indications for patients with pancreatic head cancer. By reviewing the MIPD- vs. OPD-related literature, we found that MIPD shows noninferiority or superiority to OPD in terms of safety, feasibility, enhanced recovery after surgery (ERAS) and several short-term and long-term outcomes. In addition, we analyzed and summarized the different MIPD outcomes in the USA, Europe and China. Certain debates over MIPD have continued, however, selection bias, the large number of low-volume centers, the steep MIPD learning curve, high conversion rate and administration of neoadjuvant therapy may limit the application of MIPD for pancreatic head cancer. AME Publishing Company 2019-12 /pmc/articles/PMC6955167/ /pubmed/31949389 http://dx.doi.org/10.21147/j.issn.1000-9604.2019.06.03 Text en Copyright © 2019 Chinese Journal of Cancer Research. All rights reserved. http://creativecommons.org/licenses/by-nc-sa/4.0/ This work is licensed under a Creative Commons Attribution-Non Commercial-Share Alike 4.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/4.0/
spellingShingle Review Article
Feng, Mengyu
Cao, Zhe
Sun, Zhiwei
Zhang, Taiping
Zhao, Yupei
Pancreatic head cancer: Open or minimally invasive pancreaticoduodenectomy?
title Pancreatic head cancer: Open or minimally invasive pancreaticoduodenectomy?
title_full Pancreatic head cancer: Open or minimally invasive pancreaticoduodenectomy?
title_fullStr Pancreatic head cancer: Open or minimally invasive pancreaticoduodenectomy?
title_full_unstemmed Pancreatic head cancer: Open or minimally invasive pancreaticoduodenectomy?
title_short Pancreatic head cancer: Open or minimally invasive pancreaticoduodenectomy?
title_sort pancreatic head cancer: open or minimally invasive pancreaticoduodenectomy?
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955167/
https://www.ncbi.nlm.nih.gov/pubmed/31949389
http://dx.doi.org/10.21147/j.issn.1000-9604.2019.06.03
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