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CDK6 inhibits lymphoid cell infiltration and represents a prognostic marker in HPV+ squamous cell carcinoma of head and neck

OBJECTIVE: We investigated the correlations between cyclin-dependent kinase 4/6 (CDK4/6) levels and human papillomavirus (HPV) infection state in head and neck squamous cell cancer (HNSCC). The aim was to explore the potential value of CDK4/6 inhibitors in the treatment of HNSCC. METHODS: Multiomic...

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Detalles Bibliográficos
Autores principales: Tang, Chuanhao, Lin, Li, Zhou, Wei, Liu, Xiang, Fu, Yali, Zhang, Lingling, Li, Li, Wang, Xiangyi, Zhao, Libo, Liang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955169/
https://www.ncbi.nlm.nih.gov/pubmed/31949392
http://dx.doi.org/10.21147/j.issn.1000-9604.2019.06.06