Cargando…

CDK6 inhibits lymphoid cell infiltration and represents a prognostic marker in HPV+ squamous cell carcinoma of head and neck

OBJECTIVE: We investigated the correlations between cyclin-dependent kinase 4/6 (CDK4/6) levels and human papillomavirus (HPV) infection state in head and neck squamous cell cancer (HNSCC). The aim was to explore the potential value of CDK4/6 inhibitors in the treatment of HNSCC. METHODS: Multiomic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tang, Chuanhao, Lin, Li, Zhou, Wei, Liu, Xiang, Fu, Yali, Zhang, Lingling, Li, Li, Wang, Xiangyi, Zhao, Libo, Liang, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955169/ https://www.ncbi.nlm.nih.gov/pubmed/31949392 http://dx.doi.org/10.21147/j.issn.1000-9604.2019.06.06

Ejemplares similares

Characteristics of B lymphocyte infiltration in HPV(+) head and neck squamous cell carcinoma
por: Zhang, Siwei, et al.
Publicado: (2021)

Metformin Clinical Trial in HPV+ and HPV– Head and Neck Squamous Cell Carcinoma: Impact on Cancer Cell Apoptosis and Immune Infiltrate
por: Curry, Joseph M., et al.
Publicado: (2018)

The radiobiology of HPV-positive and HPV-negative head and neck squamous cell carcinoma
por: Zhou, Chumin, et al.
Publicado: (2020)

Radioimmunotherapy in HPV-Associated Head and Neck Squamous Cell Carcinoma
por: Zhou, Xin, et al.
Publicado: (2022)

Comprehensive analysis of mitophagy in HPV-related head and neck squamous cell carcinoma
por: Yanan, Li, et al.
Publicado: (2023)

CDK7 Predicts Worse Outcome in Head and Neck Squamous-Cell Cancer
por: Jagomast, Tobias, et al.
Publicado: (2022)

Proteome and phosphoproteome signatures of recurrence for HPV(+) head and neck squamous cell carcinoma
por: Kaneko, Tomonori, et al.
Publicado: (2022)

Profiles of immune cell infiltration in head and neck squamous carcinoma
por: Liang, Bin, et al.
Publicado: (2020)

Advancements in the Management of HPV-Associated Head and Neck Squamous Cell Carcinoma
por: Zeitlin, Ross, et al.
Publicado: (2015)

HPV Detection in Head and Neck Squamous Cell Carcinomas: What Is the Issue?
por: Augustin, Jeremy Gbenakpon, et al.
Publicado: (2020)

An Immunocompetent Mouse Model of HPV16(+) Head and Neck Squamous Cell Carcinoma
por: Carper, Miranda B., et al.
Publicado: (2019)

Cisplatin exposure causes c-Myc-dependent resistance to CDK4/6 inhibition in HPV-negative head and neck squamous cell carcinoma
por: Robinson, Anthony M., et al.
Publicado: (2019)

TYK2 correlates with immune infiltration: A prognostic marker for head and neck squamous cell carcinoma
por: He, Yaodong, et al.
Publicado: (2022)

Adaptive immune resistance in HPV-associated head and neck squamous cell carcinoma
por: Pai, Sara I.
Publicado: (2013)

Management of HPV-Related Squamous Cell Carcinoma of the Head and Neck: Pitfalls and Caveat
por: Perri, Francesco, et al.
Publicado: (2020)

PYHIN Proteins and HPV: Role in the Pathogenesis of Head and Neck Squamous Cell Carcinoma
por: Riva, Giuseppe, et al.
Publicado: (2019)

Therapeutic strategies of different HPV status in Head and Neck Squamous Cell Carcinoma
por: Sun, Yingming, et al.
Publicado: (2021)

De-Escalating Strategies in HPV-Associated Head and Neck Squamous Cell Carcinoma
por: Economopoulou, Panagiota, et al.
Publicado: (2021)

Mechanisms of Cisplatin Resistance in HPV Negative Head and Neck Squamous Cell Carcinomas
por: Griso, Ana Belén, et al.
Publicado: (2022)

Radiosensitization approaches for HPV‐positive and HPV‐negative head and neck squamous carcinomas
por: Dok, Rüveyda, et al.
Publicado: (2019)

CTHRC1 is associated with immune cell infiltration and functions as an adverse marker for prognosis in head and neck squamous cell carcinoma
por: Zhong, Ruolei, et al.
Publicado: (2023)

Distinct patterns of intratumoral immune cell infiltrates in patients with HPV-associated compared to non-virally induced head and neck squamous cell carcinoma
por: Partlová, Simona, et al.
Publicado: (2015)

A Tumor-Infiltration CD8+ T Cell-Based Gene Signature for Facilitating the Prognosis and Estimation of Immunization Responses in HPV+ Head and Neck Squamous Cell Cancer
por: Wu, Yingning, et al.
Publicado: (2021)

DOCK8 Serves as a Prognostic Biomarker and Is Related to Immune Infiltration in Patients With HPV Positive Head and Neck Squamous Cell Carcinoma
por: Zhang, Zeying, et al.
Publicado: (2021)

β-CATENIN is a positive prognostic marker for HPV-positive head and neck squamous cell carcinoma
por: Stoiber, Stefan, et al.
Publicado: (2023)

Identification novel prognostic signatures for Head and Neck Squamous Cell Carcinoma based on ceRNA network construction and immune infiltration analysis
por: Zhou, Haiting, et al.
Publicado: (2021)

Single-Cell Transcriptome Analysis Reveals Different Immune Signatures in HPV- and HPV + Driven Human Head and Neck Squamous Cell Carcinoma
por: Li, Simin, et al.
Publicado: (2022)

B cell signatures and tertiary lymphoid structures contribute to outcome in head and neck squamous cell carcinoma
por: Ruffin, Ayana T., et al.
Publicado: (2021)

In vitro effects of gamma-secretase inhibition in HPV-positive and HPV-negative head and neck squamous cell carcinoma
por: Varatanovic, Sara, et al.
Publicado: (2023)

The Follicular Dendritic Cells and HPV 18 Interrelation in Head and Neck Squamous Cell Carcinomas of the Larynx
por: Boia, Eugen Radu, et al.
Publicado: (2023)

Tumour-infiltrating lymphocytes in the risk stratification of squamous cell carcinoma of the head and neck
por: Jones, T M
Publicado: (2014)

Pyroptosis patterns and immune infiltrates characterization in head and neck squamous cell carcinoma
por: Deng, Hongxia, et al.
Publicado: (2022)

Induction of heparanase by HPV E6 oncogene in head and neck squamous cell carcinoma
por: Hirshoren, Nir, et al.
Publicado: (2014)

Identification and functional validation of HPV-mediated hypermethylation in head and neck squamous cell carcinoma
por: Lechner, Matthias, et al.
Publicado: (2013)

Oncolytic activity of reovirus in HPV positive and negative head and neck squamous cell carcinoma
por: Cooper, Timothy, et al.
Publicado: (2015)

HPV, tumour metabolism and novel target identification in head and neck squamous cell carcinoma
por: Fleming, Jason C., et al.
Publicado: (2019)

Unique DNA methylation signature in HPV-positive head and neck squamous cell carcinomas
por: Degli Esposti, Davide, et al.
Publicado: (2017)

HPV Involvement in the Tumor Microenvironment and Immune Treatment in Head and Neck Squamous Cell Carcinomas
por: Lechien, Jérôme R., et al.
Publicado: (2020)

Active HPV infection and its influence on survival in head and neck squamous-cell cancer
por: Janecka-Widła, Anna, et al.
Publicado: (2020)

A HPV16-related prognostic indicator for head and neck squamous cell carcinoma
por: Zhang, Qian, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_t0nq12adptbo1mn0c79835tcbq