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Bone marrow mesenchymal stem cell-secreted exosomes carrying microRNA-125b protect against myocardial ischemia reperfusion injury via targeting SIRT7

MicroRNA-125b (miR-125b) reduces myocardial infarct area and restrains myocardial ischemia reperfusion injury (I/R). In this study, we aimed to investigate the effect of bone marrow mesenchymal stem cell (BMSC)-derived exosomes carrying miR-125b on I/R rats. The myocardial I/R model in rats was cons...

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Detalles Bibliográficos
Autores principales: Chen, Qi, Liu, Yu, Ding, Xueyan, Li, Qinfeng, Qiu, Fuyu, Wang, Meihui, Shen, Zhida, Zheng, Hao, Fu, Guosheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955239/
https://www.ncbi.nlm.nih.gov/pubmed/31858380
http://dx.doi.org/10.1007/s11010-019-03671-z