Cargando…

Sestrins are evolutionarily conserved mediators of exercise benefits

Exercise is among the most effective interventions for age-associated mobility decline and metabolic dysregulation. Although long-term endurance exercise promotes insulin sensitivity and expands respiratory capacity, genetic components and pathways mediating the metabolic benefits of exercise have r...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Myungjin, Sujkowski, Alyson, Namkoong, Sim, Gu, Bondong, Cobb, Tyler, Kim, Boyoung, Kowalsky, Allison H., Cho, Chun-Seok, Semple, Ian, Ro, Seung-Hyun, Davis, Carol, Brooks, Susan V., Karin, Michael, Wessells, Robert J., Lee, Jun Hee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955242/ https://www.ncbi.nlm.nih.gov/pubmed/31929512 http://dx.doi.org/10.1038/s41467-019-13442-5

Ejemplares similares

Exercise and Sestrin Mediate Speed and Lysosomal Activity in Drosophila by Partially Overlapping Mechanisms
por: Sujkowski, Alyson, et al.
Publicado: (2021)

Sestrin regulates acute chill coma recovery in Drosophila melanogaster
por: Cobb, Tyler, et al.
Publicado: (2021)

Variation in mobility and exercise adaptations between Drosophila species
por: Cobb, Tyler, et al.
Publicado: (2020)

Concurrent activation of growth factor and nutrient arms of mTORC1 induces oxidative liver injury
por: Cho, Chun-Seok, et al.
Publicado: (2019)

Tumor suppressive role of sestrin2 during colitis and colon carcinogenesis
por: Ro, Seung-Hyun, et al.
Publicado: (2016)

Hepatoprotective role of Sestrin2 against chronic ER stress
por: Park, Hwan-Woo, et al.
Publicado: (2014)

Muscular Sestrins: Roles in Exercise Physiology and Stress Resistance
por: Hwang, Irene, et al.
Publicado: (2023)

Sestrin2 inhibits mTORC1 through modulation of GATOR complexes
por: Kim, Jeong Sig, et al.
Publicado: (2015)

Iditarod, a Drosophila homolog of the Irisin precursor FNDC5, is critical for exercise performance and cardiac autophagy
por: Cobb, Tyler, et al.
Publicado: (2023)

Using Drosophila to Understand Biochemical and Behavioral Responses to Exercise
por: Sujkowski, Alyson, et al.
Publicado: (2018)

Corrigendum: Sestrin2 inhibits mTORC1 through modulation of GATOR complexes
por: Sig Kim, Jeong, et al.
Publicado: (2015)

Sestrin2, a Regulator of Thermogenesis and Mitohormesis in Brown Adipose Tissue
por: Ro, Seung-Hyun, et al.
Publicado: (2015)

Sestrins regulate muscle stem cell metabolic homeostasis
por: Yang, Benjamin A., et al.
Publicado: (2021)

Delayed Induction of Human NTE (PNPLA6) Rescues Neurodegeneration and Mobility Defects of Drosophila swiss cheese (sws) Mutants
por: Sujkowski, Alyson, et al.
Publicado: (2015)

Endurance exercise and selective breeding for longevity extend Drosophila healthspan by overlapping mechanisms
por: Sujkowski, Alyson, et al.
Publicado: (2015)

Alpha- and beta-adrenergic octopamine receptors in muscle and heart are required for Drosophila exercise adaptations
por: Sujkowski, Alyson, et al.
Publicado: (2020)

Endurance exercise ameliorates phenotypes in Drosophila models of spinocerebellar ataxias
por: Sujkowski, Alyson, et al.
Publicado: (2022)

SESTRINs: Emerging Dynamic Stress-Sensors in Metabolic and Environmental Health
por: Ro, Seung-Hyun, et al.
Publicado: (2020)

The Drosophila PGC-1α Homolog spargel Modulates the Physiological Effects of Endurance Exercise
por: Tinkerhess, Martin J., et al.
Publicado: (2012)

dFatp regulates nutrient distribution and long-term physiology in Drosophila
por: Sujkowski, Alyson, et al.
Publicado: (2012)

An Evolutionarily Conserved Sexual Signature in the Primate Brain
por: Reinius, Björn, et al.
Publicado: (2008)

Prediction of evolutionarily conserved interologs in Mus musculus
por: Yellaboina, Sailu, et al.
Publicado: (2008)

Conserved developmental transcriptomes in evolutionarily divergent species
por: Parikh, Anup, et al.
Publicado: (2010)

Evolutionarily Conserved Herpesviral Protein Interaction Networks
por: Fossum, Even, et al.
Publicado: (2009)

Sirtuins Are Evolutionarily Conserved Viral Restriction Factors
por: Koyuncu, Emre, et al.
Publicado: (2014)

An evolutionarily conserved pathway controls proteasome homeostasis
por: Rousseau, Adrien, et al.
Publicado: (2016)

Characterization of Evolutionarily Conserved MicroRNAs in Amphioxus
por: Wang, Lei, et al.
Publicado: (2010)

TSPO: An Evolutionarily Conserved Protein with Elusive Functions
por: Bonsack, Frederick, et al.
Publicado: (2018)

Autism sensory dysfunction in an evolutionarily conserved system
por: Vilidaite, Greta, et al.
Publicado: (2018)

Persulfide Biosynthesis Conserved Evolutionarily in All Organisms
por: Ogata, Seiryo, et al.
Publicado: (2023)

The impact of food availability on tumorigenesis is evolutionarily conserved
por: Tissot, Sophie, et al.
Publicado: (2023)

Evolutionarily Conserved Histone Methylation Dynamics during Seed Life-Cycle Transitions
por: Müller, Kerstin, et al.
Publicado: (2012)

Stress granules dynamics: benefits in cancer
por: Lee, Jeong In, et al.
Publicado: (2022)

Two evolutionarily conserved sequence elements for Peg3/Usp29 transcription
por: Kim, Jeong Do, et al.
Publicado: (2008)

Lifespan Regulation by Evolutionarily Conserved Genes Essential for Viability
por: Curran, Sean P, et al.
Publicado: (2007)

Linkage disequilibrium of evolutionarily conserved regions in the human genome
por: Kato, Mamoru, et al.
Publicado: (2006)

Identification of evolutionarily conserved genetic regulators of cellular aging
por: Laschober, Gerhard T, et al.
Publicado: (2010)

Evolutionarily Conserved Network Properties of Intrinsically Disordered Proteins
por: Rangarajan, Nivedita, et al.
Publicado: (2015)

Evolutionarily conserved mechanisms for the selection and maintenance of behavioural activity
por: Fiore, Vincenzo G., et al.
Publicado: (2015)

Epigenetic Pattern on the Human Y Chromosome Is Evolutionarily Conserved
por: Zhang, Minjie, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_5gv9gl3hh3pg2pum2gmja7990i