Physiologically based pharmacokinetic evaluation of cefuroxime in perioperative antibiotic prophylaxis

AIMS: Adequate plasma concentrations of antibiotics during surgery are essential for the prevention of surgical site infections. We examined the pharmacokinetics of 1.5 g cefuroxime administered during induction of anaesthesia with follow‐up doses every 2.5 hours until the end of surgery. We built a...

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Detalles Bibliográficos
Autores principales: Rimmler, Christer, Lanckohr, Christian, Akamp, Ceren, Horn, Dagmar, Fobker, Manfred, Wiebe, Karsten, Redwan, Bassam, Ellger, Bjoern, Koeck, Robin, Hempel, Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955413/
https://www.ncbi.nlm.nih.gov/pubmed/31487057
http://dx.doi.org/10.1111/bcp.14121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955413/
https://www.ncbi.nlm.nih.gov/pubmed/31487057
http://dx.doi.org/10.1111/bcp.14121

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