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Is age‐related increase of chromosome segregation errors in mammalian oocytes caused by cohesin deterioration?
BACKGROUND: Mammalian oocytes initiate meiosis in fetal ovary and are arrested at dictyate stage in prophase I for a long period. It is known that incidence of chromosome segregation errors in oocytes increases with advancing age, but the molecular mechanism underlying this phenomenon has not been c...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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John Wiley and Sons Inc.
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955592/ https://www.ncbi.nlm.nih.gov/pubmed/31956283 http://dx.doi.org/10.1002/rmb2.12299 |