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Comparison of Aggregated N-of-1 Trials with Parallel and Crossover Randomized Controlled Trials Using Simulation Studies

Background: N-of-1 trials offer an innovative approach to delivering personalized clinical care together with population-level research. While increasingly used, these methods have raised some statistical concerns in the healthcare community. Methods: We discuss concerns of selection bias, carryover...

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Detalles Bibliográficos
Autores principales:	Blackston, J. Walker, Chapple, Andrew G., McGree, James M., McDonald, Suzanne, Nikles, Jane
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955665/ https://www.ncbi.nlm.nih.gov/pubmed/31698799 http://dx.doi.org/10.3390/healthcare7040137

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