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Long Term Results of Modified Intersphincteric Resections for Low Rectal Cancer: A Single Center Experience

Background and Objectives: The objective of this article is to evaluate the long-term oncological and functional outcomes following modified intersphincteric resections (ISR) for low rectal cancer. The modified technique consisted of the abandonment of colonic J-pouches, transverse coloplasty, or de...

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Autores principales: Butiurca, Vlad-Olimpiu, Molnar, Călin, Constantin, Copotoiu, Botoncea, Marian, Bud, Teodor Ioan, Kovacs, Zsolt, Satala, Cătălin, Gurzu, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955682/
https://www.ncbi.nlm.nih.gov/pubmed/31795439
http://dx.doi.org/10.3390/medicina55120764
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author Butiurca, Vlad-Olimpiu
Molnar, Călin
Constantin, Copotoiu
Botoncea, Marian
Bud, Teodor Ioan
Kovacs, Zsolt
Satala, Cătălin
Gurzu, Simona
author_facet Butiurca, Vlad-Olimpiu
Molnar, Călin
Constantin, Copotoiu
Botoncea, Marian
Bud, Teodor Ioan
Kovacs, Zsolt
Satala, Cătălin
Gurzu, Simona
author_sort Butiurca, Vlad-Olimpiu
collection PubMed
description Background and Objectives: The objective of this article is to evaluate the long-term oncological and functional outcomes following modified intersphincteric resections (ISR) for low rectal cancer. The modified technique consisted of the abandonment of colonic J-pouches, transverse coloplasty, or defunctioning temporary stoma in favor of a direct handsewn coloanal anastomosis (CAA). Material and Methods: Sixty consecutive patients with type II and III (juxta-anal or intra-anal) low rectal tumors underwent modified ISR by the same surgical team and were followed for a period of five years. Functional outcomes using the Wexner Score, postoperative complications, recurrence rates, morbidity, and mortality rates were assessed. Results: The five-year survival rate was 93.3% with a disease-free interval at three years of 98%. Morbidity was 15% (n = 9) consisting of intestinal wall necrosis (n = 6), stenosis (n = 2), and sacral metastasis (n = 1). The Wexner score values were, at 1 year, 8.5 (range, 4–13); at three years 7.2 (range, 2–11); and at 5 years 6.7 (range, 2–12). A second surgery was needed in only one case that showed postoperative transmural necrosis of the colonic wall. Conclusions: In highly selected patients with type II or III low rectal tumors and proper preoperative imaging staging, ISR might be a viable alternative to other techniques such as abdominoperineal resection and low anterior resection, both from a functional and an oncological perspective.
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spelling pubmed-69556822020-01-23 Long Term Results of Modified Intersphincteric Resections for Low Rectal Cancer: A Single Center Experience Butiurca, Vlad-Olimpiu Molnar, Călin Constantin, Copotoiu Botoncea, Marian Bud, Teodor Ioan Kovacs, Zsolt Satala, Cătălin Gurzu, Simona Medicina (Kaunas) Article Background and Objectives: The objective of this article is to evaluate the long-term oncological and functional outcomes following modified intersphincteric resections (ISR) for low rectal cancer. The modified technique consisted of the abandonment of colonic J-pouches, transverse coloplasty, or defunctioning temporary stoma in favor of a direct handsewn coloanal anastomosis (CAA). Material and Methods: Sixty consecutive patients with type II and III (juxta-anal or intra-anal) low rectal tumors underwent modified ISR by the same surgical team and were followed for a period of five years. Functional outcomes using the Wexner Score, postoperative complications, recurrence rates, morbidity, and mortality rates were assessed. Results: The five-year survival rate was 93.3% with a disease-free interval at three years of 98%. Morbidity was 15% (n = 9) consisting of intestinal wall necrosis (n = 6), stenosis (n = 2), and sacral metastasis (n = 1). The Wexner score values were, at 1 year, 8.5 (range, 4–13); at three years 7.2 (range, 2–11); and at 5 years 6.7 (range, 2–12). A second surgery was needed in only one case that showed postoperative transmural necrosis of the colonic wall. Conclusions: In highly selected patients with type II or III low rectal tumors and proper preoperative imaging staging, ISR might be a viable alternative to other techniques such as abdominoperineal resection and low anterior resection, both from a functional and an oncological perspective. MDPI 2019-11-29 /pmc/articles/PMC6955682/ /pubmed/31795439 http://dx.doi.org/10.3390/medicina55120764 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Butiurca, Vlad-Olimpiu
Molnar, Călin
Constantin, Copotoiu
Botoncea, Marian
Bud, Teodor Ioan
Kovacs, Zsolt
Satala, Cătălin
Gurzu, Simona
Long Term Results of Modified Intersphincteric Resections for Low Rectal Cancer: A Single Center Experience
title Long Term Results of Modified Intersphincteric Resections for Low Rectal Cancer: A Single Center Experience
title_full Long Term Results of Modified Intersphincteric Resections for Low Rectal Cancer: A Single Center Experience
title_fullStr Long Term Results of Modified Intersphincteric Resections for Low Rectal Cancer: A Single Center Experience
title_full_unstemmed Long Term Results of Modified Intersphincteric Resections for Low Rectal Cancer: A Single Center Experience
title_short Long Term Results of Modified Intersphincteric Resections for Low Rectal Cancer: A Single Center Experience
title_sort long term results of modified intersphincteric resections for low rectal cancer: a single center experience
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955682/
https://www.ncbi.nlm.nih.gov/pubmed/31795439
http://dx.doi.org/10.3390/medicina55120764
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