Cargando…

Bismuth-Doped Nanohydroxyapatite Coatings on Titanium Implants for Improved Radiopacity and Antimicrobial Activity

This study aims to present the possibility to obtain bismuth-doped nanohydroxyapatite coatings on the surface of the titanium implants by using a solution-derived process according to an established biomimetic methodology. The bioactivity of the titanium surface was increased by an alkali-thermal tr...

Descripción completa

Detalles Bibliográficos
Autores principales: Ciobanu, Gabriela, Harja, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955781/
https://www.ncbi.nlm.nih.gov/pubmed/31783686
http://dx.doi.org/10.3390/nano9121696
_version_ 1783487007601721344
author Ciobanu, Gabriela
Harja, Maria
author_facet Ciobanu, Gabriela
Harja, Maria
author_sort Ciobanu, Gabriela
collection PubMed
description This study aims to present the possibility to obtain bismuth-doped nanohydroxyapatite coatings on the surface of the titanium implants by using a solution-derived process according to an established biomimetic methodology. The bioactivity of the titanium surface was increased by an alkali-thermal treatment. Then, under biomimetic conditions, the titanium surface was coated with a Bi-doped nanohydroxyapatite layer by using a modified supersaturated calcification solution (SCS) containing a bismuth salt. The apatite deposits were analyzed by scanning electron microscopy coupled with X-ray analysis (SEM-EDX), X-ray photoelectron spectroscopy (XPS), X-ray diffraction (XRD), and digital X-rays radiography method. The results indicate that the Bi-doped nanohydroxyapatite coatings on titanium surface were produced. These coatings exhibit a good radiopacity, thus enhancing their applications in dental and orthopedic fields. Additionally, the Bi-doped nanohydroxyapatite coatings show significant antimicrobial activity against Escherichia coli and Staphylococcus aureus bacteria.
format Online
Article
Text
id pubmed-6955781
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-69557812020-01-23 Bismuth-Doped Nanohydroxyapatite Coatings on Titanium Implants for Improved Radiopacity and Antimicrobial Activity Ciobanu, Gabriela Harja, Maria Nanomaterials (Basel) Article This study aims to present the possibility to obtain bismuth-doped nanohydroxyapatite coatings on the surface of the titanium implants by using a solution-derived process according to an established biomimetic methodology. The bioactivity of the titanium surface was increased by an alkali-thermal treatment. Then, under biomimetic conditions, the titanium surface was coated with a Bi-doped nanohydroxyapatite layer by using a modified supersaturated calcification solution (SCS) containing a bismuth salt. The apatite deposits were analyzed by scanning electron microscopy coupled with X-ray analysis (SEM-EDX), X-ray photoelectron spectroscopy (XPS), X-ray diffraction (XRD), and digital X-rays radiography method. The results indicate that the Bi-doped nanohydroxyapatite coatings on titanium surface were produced. These coatings exhibit a good radiopacity, thus enhancing their applications in dental and orthopedic fields. Additionally, the Bi-doped nanohydroxyapatite coatings show significant antimicrobial activity against Escherichia coli and Staphylococcus aureus bacteria. MDPI 2019-11-27 /pmc/articles/PMC6955781/ /pubmed/31783686 http://dx.doi.org/10.3390/nano9121696 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ciobanu, Gabriela
Harja, Maria
Bismuth-Doped Nanohydroxyapatite Coatings on Titanium Implants for Improved Radiopacity and Antimicrobial Activity
title Bismuth-Doped Nanohydroxyapatite Coatings on Titanium Implants for Improved Radiopacity and Antimicrobial Activity
title_full Bismuth-Doped Nanohydroxyapatite Coatings on Titanium Implants for Improved Radiopacity and Antimicrobial Activity
title_fullStr Bismuth-Doped Nanohydroxyapatite Coatings on Titanium Implants for Improved Radiopacity and Antimicrobial Activity
title_full_unstemmed Bismuth-Doped Nanohydroxyapatite Coatings on Titanium Implants for Improved Radiopacity and Antimicrobial Activity
title_short Bismuth-Doped Nanohydroxyapatite Coatings on Titanium Implants for Improved Radiopacity and Antimicrobial Activity
title_sort bismuth-doped nanohydroxyapatite coatings on titanium implants for improved radiopacity and antimicrobial activity
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955781/
https://www.ncbi.nlm.nih.gov/pubmed/31783686
http://dx.doi.org/10.3390/nano9121696
work_keys_str_mv AT ciobanugabriela bismuthdopednanohydroxyapatitecoatingsontitaniumimplantsforimprovedradiopacityandantimicrobialactivity
AT harjamaria bismuthdopednanohydroxyapatitecoatingsontitaniumimplantsforimprovedradiopacityandantimicrobialactivity