Cargando…

Attenuation of Benign Prostatic Hyperplasia by Optimized Tadalafil Loaded Pumpkin Seed Oil-Based Self Nanoemulsion: In Vitro and In Vivo Evaluation

The FDA has approved tadalafil (TDL) for the treatment of benign prostatic hyperplasia (BPH)-associated symptoms. Pumpkin seed oil (PSO) has shown promise for the relief of prostatitis-related lower urinary tract symptoms. The aim was to improve TDL delivery to the prostate and assess the combined e...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alhakamy, Nabil A., Fahmy, Usama A., Ahmed, Osama A. A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955804/ https://www.ncbi.nlm.nih.gov/pubmed/31805693 http://dx.doi.org/10.3390/pharmaceutics11120640

Ejemplares similares

Development and optimization of a tamsulosin nanostructured lipid carrier loaded with saw palmetto oil and pumpkin seed oil for treatment of benign prostatic hyperplasia
por: Bakhaidar, Rana B., et al.
Publicado: (2022)

Effects of pumpkin seed oil and saw palmetto oil in Korean men with symptomatic benign prostatic hyperplasia
por: Hong, Heeok, et al.
Publicado: (2009)

Pumpkin Oil–Based Nanostructured Lipid Carrier System for Antiulcer Effect in NSAID-Induced Gastric Ulcer Model in Rats
por: Ahmed, Osama A A, et al.
Publicado: (2020)

Development and In Vitro Evaluation of 2-Methoxyestradiol Loaded Polymeric Micelles for Enhancing Anticancer Activities in Prostate Cancer
por: Alhakamy, Nabil A., et al.
Publicado: (2021)

Combination of tadalafil and finasteride for improving the symptoms of benign prostatic hyperplasia: critical appraisal and patient focus
por: Elkelany, Osama O, et al.
Publicado: (2015)

Development, optimization and characterization of nanoemulsion loaded with clove oil-naftifine antifungal for the management of tinea
por: Alghaith, Adel F., et al.
Publicado: (2021)

Measurement properties of the benign prostatic hyperplasia impact index in tadalafil studies
por: Angalakuditi, Mallik, et al.
Publicado: (2010)

Effects of an Oil-Free Hydroethanolic Pumpkin Seed Extract on Symptom Frequency and Severity in Men with Benign Prostatic Hyperplasia: A Pilot Study in Humans
por: Leibbrand, Martin, et al.
Publicado: (2019)

Pumpkin seed oil (Cucurbita pepo) versus tamsulosin for benign prostatic hyperplasia symptom relief: a single-blind randomized clinical trial
por: Zerafatjou, Nikan, et al.
Publicado: (2021)

Coconut Oil Nanoemulsion Loaded with a Statin Hypolipidemic Drug for Management of Burns: Formulation and In Vivo Evaluation
por: Hosny, Khaled M., et al.
Publicado: (2020)

Oil of Pumpkin Seeds in Tape Worm
por: Patterson, Henry S.
Publicado: (1853)

Omega-3 Self-Nanoemulsion Role in Gastroprotection against Indomethacin-Induced Gastric Injury in Rats
por: Ahmed, Osama A. A., et al.
Publicado: (2020)

Meta-Analysis of Efficacy and Safety of Tadalafil Plus Tamsulosin Compared with Tadalafil Alone in Treating Men with Benign Prostatic Hyperplasia and Erectile Dysfunction
por: Zhou, Zhongbao, et al.
Publicado: (2019)

On the Treatment of Tape-Worm by the Oil of Pumpkin-Seeds
Publicado: (1853)

Optimization of Thymoquinone-Loaded Self-Nanoemulsion for Management of Indomethacin-Induced Ulcer
por: Radwan, Mohamed F., et al.
Publicado: (2021)

Green Nanoemulsion Stabilized by In Situ Self-Assembled Natural Oil/Native Cyclodextrin Complexes: An Eco-Friendly Approach for Enhancing Anticancer Activity of Costunolide against Lung Cancer Cells
por: Alhakamy, Nabil A., et al.
Publicado: (2022)

Development, Optimization and Evaluation of 2-Methoxy-Estradiol Loaded Nanocarrier for Prostate Cancer
por: Alhakamy, Nabil A., et al.
Publicado: (2021)

Fluoxetine Ecofriendly Nanoemulsion Enhances Wound Healing in Diabetic Rats: In Vivo Efficacy Assessment
por: Alhakamy, Nabil A., et al.
Publicado: (2022)

The use of a single daily dose of tadalafil to treat signs and symptoms of benign prostatic hyperplasia and erectile dysfunction
por: Gacci, Mauro, et al.
Publicado: (2013)

Vitamin E TPGS based transferosomes augmented TAT as a promising delivery system for improved transdermal delivery of raloxifene
por: Alhakamy, Nabil A., et al.
Publicado: (2019)

Trans-perineal pumpkin seed oil phonophoresis as an adjunctive treatment for chronic nonbacterial prostatitis
por: Tantawy, Sayed A, et al.
Publicado: (2018)

Phytosterols in hull-less pumpkin seed oil, rich in ∆(7)-phytosterols, ameliorate benign prostatic hyperplasia by lowing 5α-reductase and regulating balance between cell proliferation and apoptosis in rats
por: Kang, Xin-cong, et al.
Publicado: (2021)

Self-Nanoemulsion Loaded with a Combination of Isotretinoin, an Anti-Acne Drug, and Quercetin: Preparation, Optimization, and In Vivo Assessment
por: Hosny, Khaled M., et al.
Publicado: (2020)

Management options for the treatment of benign prostatic hyperplasia with or without erectile dysfunction: a focus on tadalafil and patient considerations
por: Alsaikhan, Bader, et al.
Publicado: (2014)

The potential role of pumpkin seeds oil on methotrexate-induced lung toxicity
por: Abosrea, Aya M., et al.
Publicado: (2023)

Optimized Icariin Cubosomes Exhibit Augmented Cytotoxicity against SKOV-3 Ovarian Cancer Cells
por: Fahmy, Usama A., et al.
Publicado: (2020)

Pumpkin Seed in Tenia
Publicado: (1855)

Oral gel loaded with penciclovir–lavender oil nanoemulsion to enhance bioavailability and alleviate pain associated with herpes labialis
por: Hosny, Khaled M., et al.
Publicado: (2021)

Apamin-Conjugated Alendronate Sodium Nanocomplex for Management of Pancreatic Cancer
por: Alhakamy, Nabil A., et al.
Publicado: (2021)

Mastoparan, a Peptide Toxin from Wasp Venom Conjugated Fluvastatin Nanocomplex for Suppression of Lung Cancer Cell Growth
por: Alhakamy, Nabil A., et al.
Publicado: (2021)

Formulation Design, Statistical Optimization, and In Vitro Evaluation of a Naringenin Nanoemulsion to Enhance Apoptotic Activity in A549 Lung Cancer Cells
por: Md, Shadab, et al.
Publicado: (2020)

Improved effect of pumpkin seed oil against the bisphenol-A adverse effects in male mice
por: Fawzy, Eissa I., et al.
Publicado: (2018)

Urine miR-21-5p as a potential biomarker for predicting effectiveness of tadalafil in benign prostatic hyperplasia
por: Tanaka, Tomoaki, et al.
Publicado: (2018)

Improvement of the symptoms of lower urinary tract and sexual dysfunction with tadalafil and solifenacin after the treatment of benign prostatic hyperplasia with dutasteride
por: Kosilov, Kirill V., et al.
Publicado: (2020)

Efficacy and safety of dutasteride with tadalafil add-on therapy in patients with lower urinary tract symptoms secondary to benign prostatic hyperplasia
por: Gotoh, Daisuke, et al.
Publicado: (2022)

Inhibitory effects of Nigella sativa seed oil on the testosterone-induced benign prostatic hyperplasia in rats
por: Sadeghimanesh, Arezo, et al.
Publicado: (2021)

Tadalafil Nanoemulsion Mists for Treatment of Pediatric Pulmonary Hypertension via Nebulization
por: Elbardisy, Bassant, et al.
Publicado: (2022)

Development and Evaluation of Repurposed Etoricoxib Loaded Nanoemulsion for Improving Anticancer Activities against Lung Cancer Cells
por: Md, Shadab, et al.
Publicado: (2021)

Pumpkin Seeds for Tape-Worm
Publicado: (1855)

Pumpkin Seed for Tape Worm
por: Thomas, H. J.
Publicado: (1880)

Cannot write session to /tmp/vufind_sessions/sess_93a4ej59o7q2285i2ppl7pak9t