Pseudomonas aeruginosa Toxin ExoU as a Therapeutic Target in the Treatment of Bacterial Infections

The opportunistic pathogen Pseudomonas aeruginosa employs the type III secretion system (T3SS) and four effector proteins, ExoS, ExoT, ExoU, and ExoY, to disrupt cellular physiology and subvert the host’s innate immune response. Of the effector proteins delivered by the T3SS, ExoU is the most toxic....

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Detalles Bibliográficos
Autores principales: Foulkes, Daniel M., McLean, Keri, Haneef, Atikah S., Fernig, David G., Winstanley, Craig, Berry, Neil, Kaye, Stephen B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955817/
https://www.ncbi.nlm.nih.gov/pubmed/31888268
http://dx.doi.org/10.3390/microorganisms7120707

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955817/
https://www.ncbi.nlm.nih.gov/pubmed/31888268
http://dx.doi.org/10.3390/microorganisms7120707

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