Risperidone-Loaded PLGA–Lipid Particles with Improved Release Kinetics: Manufacturing and Detailed Characterization by Electron Microscopy and Nano-CT

For parenteral controlled drug release, the desired zero order release profile with no lag time is often difficult to achieve. To overcome the undesired lag time of the current commercial risperidone controlled release formulation, we developed PLGA–lipid microcapsules (MCs) and PLGA–lipid microgels...

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Detalles Bibliográficos
Autores principales: Janich, Christopher, Friedmann, Andrea, Martins de Souza e Silva, Juliana, Santos de Oliveira, Cristine, de Souza, Ligia E., Rujescu, Dan, Hildebrandt, Christian, Beck-Broichsitter, Moritz, Schmelzer, Christian E. H., Mäder, Karsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956012/
https://www.ncbi.nlm.nih.gov/pubmed/31835353
http://dx.doi.org/10.3390/pharmaceutics11120665

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