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Bioprinting for Liver Transplantation
Bioprinting techniques can be used for the in vitro fabrication of functional complex bio-structures. Thus, extensive research is being carried on the use of various techniques for the development of 3D cellular structures. This article focuses on direct writing techniques commonly used for the fabr...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956058/ https://www.ncbi.nlm.nih.gov/pubmed/31658719 http://dx.doi.org/10.3390/bioengineering6040095 |
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author | Kryou, Christina Leva, Valentina Chatzipetrou, Marianneza Zergioti, Ioanna |
author_facet | Kryou, Christina Leva, Valentina Chatzipetrou, Marianneza Zergioti, Ioanna |
author_sort | Kryou, Christina |
collection | PubMed |
description | Bioprinting techniques can be used for the in vitro fabrication of functional complex bio-structures. Thus, extensive research is being carried on the use of various techniques for the development of 3D cellular structures. This article focuses on direct writing techniques commonly used for the fabrication of cell structures. Three different types of bioprinting techniques are depicted: Laser-based bioprinting, ink-jet bioprinting and extrusion bioprinting. Further on, a special reference is made to the use of the bioprinting techniques for the fabrication of 2D and 3D liver model structures and liver on chip platforms. The field of liver tissue engineering has been rapidly developed, and a wide range of materials can be used for building novel functional liver structures. The focus on liver is due to its importance as one of the most critical organs on which to test new pharmaceuticals, as it is involved in many metabolic and detoxification processes, and the toxicity of the liver is often the cause of drug rejection. |
format | Online Article Text |
id | pubmed-6956058 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-69560582020-01-23 Bioprinting for Liver Transplantation Kryou, Christina Leva, Valentina Chatzipetrou, Marianneza Zergioti, Ioanna Bioengineering (Basel) Review Bioprinting techniques can be used for the in vitro fabrication of functional complex bio-structures. Thus, extensive research is being carried on the use of various techniques for the development of 3D cellular structures. This article focuses on direct writing techniques commonly used for the fabrication of cell structures. Three different types of bioprinting techniques are depicted: Laser-based bioprinting, ink-jet bioprinting and extrusion bioprinting. Further on, a special reference is made to the use of the bioprinting techniques for the fabrication of 2D and 3D liver model structures and liver on chip platforms. The field of liver tissue engineering has been rapidly developed, and a wide range of materials can be used for building novel functional liver structures. The focus on liver is due to its importance as one of the most critical organs on which to test new pharmaceuticals, as it is involved in many metabolic and detoxification processes, and the toxicity of the liver is often the cause of drug rejection. MDPI 2019-10-10 /pmc/articles/PMC6956058/ /pubmed/31658719 http://dx.doi.org/10.3390/bioengineering6040095 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Kryou, Christina Leva, Valentina Chatzipetrou, Marianneza Zergioti, Ioanna Bioprinting for Liver Transplantation |
title | Bioprinting for Liver Transplantation |
title_full | Bioprinting for Liver Transplantation |
title_fullStr | Bioprinting for Liver Transplantation |
title_full_unstemmed | Bioprinting for Liver Transplantation |
title_short | Bioprinting for Liver Transplantation |
title_sort | bioprinting for liver transplantation |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956058/ https://www.ncbi.nlm.nih.gov/pubmed/31658719 http://dx.doi.org/10.3390/bioengineering6040095 |
work_keys_str_mv | AT kryouchristina bioprintingforlivertransplantation AT levavalentina bioprintingforlivertransplantation AT chatzipetroumarianneza bioprintingforlivertransplantation AT zergiotiioanna bioprintingforlivertransplantation |