Personalised Medicine Using N-of-1 Trials: Overcoming Barriers to Delivery

In this paper we discuss the value of N-of-1 trials in personalising health care. We describe the challenges faced in implementing N-of-1 trials in the United Kingdom’s National Health Service and suggest how making greater use of these personalised trials might be facilitated.

Detalles Bibliográficos
Autores principales: Chalmers, Iain, Smeeth, Liam, Goldacre, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Discussion
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956166/
https://www.ncbi.nlm.nih.gov/pubmed/31694150
http://dx.doi.org/10.3390/healthcare7040134
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author Chalmers, Iain
Smeeth, Liam
Goldacre, Ben
author_facet Chalmers, Iain
Smeeth, Liam
Goldacre, Ben
author_sort Chalmers, Iain
collection PubMed
description In this paper we discuss the value of N-of-1 trials in personalising health care. We describe the challenges faced in implementing N-of-1 trials in the United Kingdom’s National Health Service and suggest how making greater use of these personalised trials might be facilitated.
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spelling pubmed-69561662020-01-23 Personalised Medicine Using N-of-1 Trials: Overcoming Barriers to Delivery Chalmers, Iain Smeeth, Liam Goldacre, Ben Healthcare (Basel) Discussion In this paper we discuss the value of N-of-1 trials in personalising health care. We describe the challenges faced in implementing N-of-1 trials in the United Kingdom’s National Health Service and suggest how making greater use of these personalised trials might be facilitated. MDPI 2019-11-05 /pmc/articles/PMC6956166/ /pubmed/31694150 http://dx.doi.org/10.3390/healthcare7040134 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Discussion
Chalmers, Iain
Smeeth, Liam
Goldacre, Ben
Personalised Medicine Using N-of-1 Trials: Overcoming Barriers to Delivery
title Personalised Medicine Using N-of-1 Trials: Overcoming Barriers to Delivery
title_full Personalised Medicine Using N-of-1 Trials: Overcoming Barriers to Delivery
title_fullStr Personalised Medicine Using N-of-1 Trials: Overcoming Barriers to Delivery
title_full_unstemmed Personalised Medicine Using N-of-1 Trials: Overcoming Barriers to Delivery
title_short Personalised Medicine Using N-of-1 Trials: Overcoming Barriers to Delivery
title_sort personalised medicine using n-of-1 trials: overcoming barriers to delivery
topic Discussion
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956166/
https://www.ncbi.nlm.nih.gov/pubmed/31694150
http://dx.doi.org/10.3390/healthcare7040134
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