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Validation of an Ex Vivo Permeation Method for the Intestinal Permeability of Different BCS Drugs and Its Correlation with Caco-2 In Vitro Experiments

The absorption study of drugs through different biological membranes constitutes an essential step in the development of new pharmaceutical dosage forms. Concerning orally administered forms, methods based on monolayer cell culture of Caco-2 (Caucasian colon adenocarcinoma) have been developed to em...

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Detalles Bibliográficos
Autores principales: B. Sánchez, Aroha, C. Calpena, Ana, Mallandrich, Mireia, Clares, Beatriz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956211/
https://www.ncbi.nlm.nih.gov/pubmed/31795506
http://dx.doi.org/10.3390/pharmaceutics11120638