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Glucose restriction combined with chemotherapy decreases telomere length and cancer antigen-125 secretion in ovarian carcinoma

Although chemotherapy is the standard treatment for ovarian cancer (OC), recent studies have focused on its coupling with hypoglycemic drugs to decrease glucose availability. Similarly to cancer antigen 125 (Ca-125), telomerase, the key protein for telomere lengthening, is overexpressed in 90% of OC...

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Detalles Bibliográficos
Autores principales: Antoun, Stephanie, Atallah, David, Tahtouh, Roula, Assaf, Mona Diab, Moubarak, Malak, Ayoub, Eliane Nasser, Chahine, Georges, Hilal, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956372/
https://www.ncbi.nlm.nih.gov/pubmed/31966066
http://dx.doi.org/10.3892/ol.2019.11233