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PLGA-BMP-2 and PLA-17β-Estradiol Microspheres Reinforcing a Composite Hydrogel for Bone Regeneration in Osteoporosis
The controlled release of active substances—bone morphogenetic protein 2 (BMP-2) and 17β-estradiol—is one of the main aspects to be taken into account to successfully regenerate a tissue defect. In this study, BMP-2- and 17β-estradiol-loaded microspheres were combined in a sandwich-like system forme...
Autores principales: | García-García, Patricia, Reyes, Ricardo, Segredo-Morales, Elisabet, Pérez-Herrero, Edgar, Delgado, Araceli, Évora, Carmen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956377/ https://www.ncbi.nlm.nih.gov/pubmed/31817033 http://dx.doi.org/10.3390/pharmaceutics11120648 |
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