Determinants of prolonged hospitalization in patients who underwent trans-femoral transcatheter aortic valve implantation

INTRODUCTION: Transcatheter aortic valve implantation (TAVI) has grown to be an alternative treatment for severe symptomatic aortic valve stenosis (AS) in elderly patients. Although TAVI is a less invasive surgery than surgical aortic valve replacement, some patients may require prolonged hospitalization. AIM: To find the determinants of prolonged hospitalization in patients who underwent trans-femoral TAVI. MATERIAL AND METHODS: A total of 94 AS patients who underwent trans-femoral TAVI were included as the final study population, and divided into the conventional hospitalization group (≤ 21 days) (n = 74) and prolonged hospitalization group (> 21 days) (n = 20). We compared clinical characteristics between the two groups, and multivariate logistic regression analysis was performed to find the determinants of prolonged hospitalization. RESULTS: In multivariate logistic regression analysis, moderate or severe mitral regurgitation (OR = 4.49, 95% CI: 1.16–17.47, p = 0.03), taking statins or angiotensin converting enzyme (ACE) inhibitors/angiotensin II receptor blockers (ARB) on admission (statins: OR = 0.13, 95% CI: 0.02–0.71, p = 0.02, ACE inhibitors/ARB: OR = 0.25, 95% CI: 0.06–0.96, p = 0.04), estimated glomerular filtration rate (eGFR) (per 15 ml/min/1.73 m(2) incremental) (OR = 0.49, 95% CI: 0.26–0.90, p = 0.02) and current chopsticks user (OR = 0.05, 95% CI: 0.01–0.41, p < 0.01) were significantly associated with prolonged hospitalization. CONCLUSIONS: Moderate or severe mitral regurgitation was significantly associated with prolonged hospitalization, while current chopsticks user, eGFR (per 15 ml/min/1.73 m(2) incremental), taking ACE inhibitors/ARB or statins before the procedure were inversely associated with prolonged hospitalization in patients who underwent trans-femoral TAVI.