Cargando…

Distinct chromophore–protein environments enable asymmetric activation of a bacteriophytochrome-activated diguanylate cyclase

Sensing of red and far-red light by bacteriophytochromes involves intricate interactions between their bilin chromophore and the protein environment. The light-triggered rearrangements of the cofactor configuration and eventually the protein conformation enable bacteriophytochromes to interact with...

Descripción completa

Detalles Bibliográficos
Autores principales:	Buhrke, David, Gourinchas, Geoffrey, Müller, Melanie, Michael, Norbert, Hildebrandt, Peter, Winkler, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2020
Materias:	Protein Structure and Folding
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956517/ https://www.ncbi.nlm.nih.gov/pubmed/31801828 http://dx.doi.org/10.1074/jbc.RA119.011915

Ejemplares similares

Structure-guided design and functional characterization of an artificial red light–regulated guanylate/adenylate cyclase for optogenetic applications
por: Etzl, Stefan, et al.
Publicado: (2018)

Structural Basis for Enzymatic Evolution from a Dedicated ADP-ribosyl Cyclase to a Multifunctional NAD Hydrolase
por: Liu, Qun, et al.
Publicado: (2009)

The S100A10-Annexin A2 Complex Provides a Novel Asymmetric Platform for Membrane Repair
por: Rezvanpour, Atoosa, et al.
Publicado: (2011)

Appearance and Propagation of Polyglutamine-based Amyloids in Yeast: TYROSINE RESIDUES ENABLE POLYMER FRAGMENTATION
por: Alexandrov, Ilya M., et al.
Publicado: (2008)

Conformational flexibility within the nascent polypeptide–associated complex enables its interactions with structurally diverse client proteins
por: Martin, Esther M., et al.
Publicado: (2018)

Distinct Agonist Regulation of Muscarinic Acetylcholine M(2)-M(3) Heteromers and Their Corresponding Homomers
por: Aslanoglou, Despoina, et al.
Publicado: (2015)

Structural analysis of the catalytic domain of Artemis endonuclease/SNM1C reveals distinct structural features
por: Karim, Md Fazlul, et al.
Publicado: (2020)

Accessory Interaction Motifs in the Atg19 Cargo Receptor Enable Strong Binding to the Clustered Ubiquitin-related Atg8 Protein
por: Abert, Christine, et al.
Publicado: (2016)

The Structure of an Interdomain Complex That Regulates Talin Activity
por: Goult, Benjamin T., et al.
Publicado: (2009)

Mapping the IκB Kinase β (IKKβ)-binding Interface of the B14 Protein, a Vaccinia Virus Inhibitor of IKKβ-mediated Activation of Nuclear Factor κB
por: Benfield, Camilla T. O., et al.
Publicado: (2011)

Interactions between Kar2p and Its Nucleotide Exchange Factors Sil1p and Lhs1p Are Mechanistically Distinct
por: Hale, Sarah J., et al.
Publicado: (2010)

Mechanism and Specificity of Pentachloropseudilin-mediated Inhibition of Myosin Motor Activity
por: Chinthalapudi, Krishna, et al.
Publicado: (2011)

Engineering Novel Complement Activity into a Pulmonary Surfactant Protein
por: Venkatraman Girija, Umakhanth, et al.
Publicado: (2010)

Conserved Distal Loop Residues in the Hsp104 and ClpB Middle Domain Contact Nucleotide-binding Domain 2 and Enable Hsp70-dependent Protein Disaggregation
por: DeSantis, Morgan E., et al.
Publicado: (2014)

Structural Basis for the Regulation of Protein Kinase A by Activation Loop Phosphorylation
por: Steichen, Jon M., et al.
Publicado: (2012)

Structural basis for the glycosyltransferase activity of the Salmonella effector SseK3
por: Esposito, Diego, et al.
Publicado: (2018)

APH1 Polar Transmembrane Residues Regulate the Assembly and Activity of Presenilin Complexes
por: Pardossi-Piquard, Raphaëlle, et al.
Publicado: (2009)

Structural Basis for Activity Regulation and Substrate Preference of Clostridial Collagenases G, H, and T
por: Eckhard, Ulrich, et al.
Publicado: (2013)

Gating control of the cardiac sodium channel Nav1.5 by its β3-subunit involves distinct roles for a transmembrane glutamic acid and the extracellular domain
por: Salvage, Samantha C., et al.
Publicado: (2019)

Electrostatic and Lipid Anchor Contributions to the Interaction of Transducin with Membranes: MECHANISTIC IMPLICATIONS FOR ACTIVATION AND TRANSLOCATION
por: Kosloff, Mickey, et al.
Publicado: (2008)

Structural Basis for the Activity and Substrate Specificity of Fluoroacetyl-CoA Thioesterase FlK
por: Dias, Marcio V. B., et al.
Publicado: (2010)

Structural Insights into the Activation of the RhoA GTPase by the Lymphoid Blast Crisis (Lbc) Oncoprotein
por: Lenoir, Marc, et al.
Publicado: (2014)

Structural characterization of anti-CCL5 activity of the tick salivary protein evasin-4
por: Denisov, Stepan S., et al.
Publicado: (2020)

C-terminal α-synuclein truncations are linked to cysteine cathepsin activity in Parkinson's disease
por: McGlinchey, Ryan P., et al.
Publicado: (2019)

Nucleotide Binding by Lhs1p Is Essential for Its Nucleotide Exchange Activity and for Function in Vivo
por: de Keyzer, Jeanine, et al.
Publicado: (2009)

Ovalbumin-related Protein X Is a Heparin-binding Ov-Serpin Exhibiting Antimicrobial Activities
por: Réhault-Godbert, Sophie, et al.
Publicado: (2013)

A model for the conformational activation of the structurally quiescent metalloprotease ADAMTS13 by von willebrand factor
por: South, Kieron, et al.
Publicado: (2017)

Amino Acid Region 1000–1008 of Factor V Is a Dynamic Regulator for the Emergence of Procoagulant Activity
por: Wiencek, Joesph R., et al.
Publicado: (2013)

Inter-domain Communication of Human Cystathionine β-Synthase: STRUCTURAL BASIS OF S-ADENOSYL-l-METHIONINE ACTIVATION
por: McCorvie, Thomas J., et al.
Publicado: (2014)

Crystal Structure of the Bacillus subtilis Phosphodiesterase PhoD Reveals an Iron and Calcium-containing Active Site
por: Rodriguez, Fernanda, et al.
Publicado: (2014)

Turnip yellow mosaic virus protease binds ubiquitin suboptimally to fine-tune its deubiquitinase activity
por: Fieulaine, Sonia, et al.
Publicado: (2020)

Structural basis of specific inhibition of extracellular activation of pro- or latent myostatin by the monoclonal antibody SRK-015
por: Dagbay, Kevin B., et al.
Publicado: (2020)

Near-planar Solution Structures of Mannose-binding Lectin Oligomers Provide Insight on Activation of Lectin Pathway of Complement
por: Miller, Ami, et al.
Publicado: (2012)

Evidence That GH115 α-Glucuronidase Activity, Which Is Required to Degrade Plant Biomass, Is Dependent on Conformational Flexibility
por: Rogowski, Artur, et al.
Publicado: (2014)

Trimeric Structure of (+)-Pinoresinol-forming Dirigent Protein at 1.95 Å Resolution with Three Isolated Active Sites
por: Kim, Kye-Won, et al.
Publicado: (2015)

Structure-Function Analyses of Human Kallikrein-related Peptidase 2 Establish the 99-Loop as Master Regulator of Activity
por: Skala, Wolfgang, et al.
Publicado: (2014)

Mechanism of vaccinia viral protein B14–mediated inhibition of IκB kinase β activation
por: Tang, Qingyu, et al.
Publicado: (2018)

Mechanical transduction of cytoplasmic-to-transmembrane-domain movements in a hyperpolarization-activated cyclic nucleotide–gated cation channel
por: Gross, Christine, et al.
Publicado: (2018)

Structural and functional studies of Arabidopsis thaliana legumain beta reveal isoform specific mechanisms of activation and substrate recognition
por: Dall, Elfriede, et al.
Publicado: (2020)

Structure of the Nuclear Factor κB-inducing Kinase (NIK) Kinase Domain Reveals a Constitutively Active Conformation
por: Liu, Jinsong, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_dgbq4nt7j19s3io00qncq0p9sj