Integrated Epigenome, Exome, and Transcriptome Analyses Reveal Molecular Subtypes and Homeotic Transformation in Uterine Fibroids

Uterine fibroids are benign myometrial smooth muscle tumors of unknown etiology that, when symptomatic, are the most common indication for hysterectomy in the United States. Unsupervised clustering of results from DNA methylation analyses segregates normal myometrium from fibroids and further segreg...

Descripción completa

Detalles Bibliográficos
Autores principales: George, Jitu Wilson, Fan, Huihui, Johnson, Benjamin, Carpenter, Tyler James, Foy, Kelly Katherine, Chatterjee, Anindita, Patterson, Amanda Lynn, Koeman, Julie, Adams, Marie, Madaj, Zachary Brian, Chesla, David, Marsh, Erica Elizabeth, Triche, Timothy Junius, Shen, Hui, Teixeira, Jose Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956710/
https://www.ncbi.nlm.nih.gov/pubmed/31851934
http://dx.doi.org/10.1016/j.celrep.2019.11.077

Ejemplares similares

Ejemplares similares