GMSimpute: a generalized two-step Lasso approach to impute missing values in label-free mass spectrum analysis

MOTIVATION: Missingness in label-free mass spectrometry is inherent to the technology. A computational approach to recover missing values in metabolomics and proteomics datasets is important. Most existing methods are designed under a particular assumption, either missing at random or under the dete...

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Detalles Bibliográficos
Autores principales: Li, Qian, Fisher, Kate, Meng, Wenjun, Fang, Bin, Welsh, Eric, Haura, Eric B, Koomen, John M, Eschrich, Steven A, Fridley, Brooke L, Chen, Y Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956786/
https://www.ncbi.nlm.nih.gov/pubmed/31199438
http://dx.doi.org/10.1093/bioinformatics/btz488

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