Lipid oversupply induces CD36 sarcolemmal translocation via dual modulation of PKCζ and TBC1D1: an early event prior to insulin resistance

Lipid oversupply may induce CD36 sarcolemmal translocation to facilitate fatty acid transport, which in turn causes dyslipidemia and type 2 diabetes. However, the underlying mechanisms of CD36 redistribution are still yet to be unraveled. Methods: High fat diet fed mice and palmitate/oleic acid-trea...

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Detalles Bibliográficos
Autores principales: Zhu, Bili, Li, Ming-Yue, Lin, Quanming, Liang, Zhicheng, Xin, Qihang, Wang, Menghuan, He, Zhendan, Wang, Xiaomei, Wu, Xuli, Chen, George G., Tong, Peter CY, Zhang, Weizhen, Liu, Li-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956797/
https://www.ncbi.nlm.nih.gov/pubmed/31938068
http://dx.doi.org/10.7150/thno.40021

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