Cargando…

MicroRNA-204-5p is a tumor suppressor and potential therapeutic target in head and neck squamous cell carcinoma

Elucidation of the molecular mechanisms governing aggressiveness of HNSCC may provide clinical therapeutic strategies for patients. In this study, a novel hub miR-204-5p functioning as tumor suppressor has been identified and explored in HNSCC. Methods: A novel hub miR-204-5p was identified based on...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhuang, Zehang, Yu, Pei, Xie, Nan, Wu, Yue, Liu, Haichao, Zhang, Ming, Tao, Yifan, Wang, Weiwang, Yin, Hanqi, Zou, Bin, Hou, Jinsong, Liu, Xiqiang, Li, Jiong, Huang, Hongzhang, Wang, Cheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956807/ https://www.ncbi.nlm.nih.gov/pubmed/31938073 http://dx.doi.org/10.7150/thno.38507

Ejemplares similares

Down-Regulation of Long Non-Coding RNA TINCR Induces Cell Dedifferentiation and Predicts Progression in Oral Squamous Cell Carcinoma
por: Zhuang, Zehang, et al.
Publicado: (2021)

Activation of adrenergic receptor β2 promotes tumor progression and epithelial mesenchymal transition in tongue squamous cell carcinoma
por: Liu, Haichao, et al.
Publicado: (2018)

Decreased miR-320a promotes invasion and metastasis of tumor budding cells in tongue squamous cell carcinoma
por: Xie, Nan, et al.
Publicado: (2016)

MicroRNA-218 promotes cisplatin resistance in oral cancer via the PPP2R5A/Wnt signaling pathway
por: Zhuang, Zehang, et al.
Publicado: (2017)

Interplay between ΔNp63 and miR-138-5p regulates growth, metastasis and stemness of oral squamous cell carcinoma
por: Zhuang, Zehang, et al.
Publicado: (2017)

MicroRNA Profiling and Head and Neck Cancer
por: Liu, Xiqiang, et al.
Publicado: (2009)

Correlate the TP53 Mutation and the HRAS Mutation with Immune Signatures in Head and Neck Squamous Cell Cancer
por: Lyu, Haoyu, et al.
Publicado: (2019)

MicroRNA‐204‐5p: A pivotal tumor suppressor
por: Yang, Fan, et al.
Publicado: (2022)

Exosomes in Head and Neck Squamous Cell Carcinoma
por: Xiao, Cheng, et al.
Publicado: (2019)

Magnetic Resonance Imaging‐Based Radiomics Features Associated with Depth of Invasion Predicted Lymph Node Metastasis and Prognosis in Tongue Cancer
por: Wang, Fei, et al.
Publicado: (2021)

miR-204 enhances p27 mRNA stability by targeting Brd4 in head and neck squamous cell carcinoma
por: Wang, Caihua, et al.
Publicado: (2018)

MicroRNA Deregulations in Head and Neck Squamous Cell Carcinomas
por: Chen, Dan, et al.
Publicado: (2013)

Loss of HOP tumour suppressor expression in head and neck squamous cell carcinoma
por: Lemaire, F, et al.
Publicado: (2004)

A Super-Enhancer Driven by FOSL1 Controls miR-21-5p Expression in Head and Neck Squamous Cell Carcinoma
por: Wan, Yuehan, et al.
Publicado: (2021)

Integrated analysis of deregulation microRNA expression in head and neck squamous cell carcinoma
por: Qi, Cheng-Lin, et al.
Publicado: (2021)

Circulating Tumor Cells Correlate With Prognosis in Head and Neck Squamous Cell Carcinoma
por: Zhou, Shichao, et al.
Publicado: (2021)

Axon guidance molecule semaphorin3A is a novel tumor suppressor in head and neck squamous cell carcinoma
por: Wang, Zhao, et al.
Publicado: (2016)

Perioperative risk factors for postoperative pneumonia after major oral cancer surgery: A retrospective analysis of 331 cases
por: Xu, Jieyun, et al.
Publicado: (2017)

An integrated bioinformatics analysis of the S100 in head and neck squamous cell carcinoma
por: Bai, Guo, et al.
Publicado: (2023)

ING Genes Work as Tumor Suppressor Genes in the Carcinogenesis of Head and Neck Squamous Cell Carcinoma
por: Li, Xiaohan, et al.
Publicado: (2011)

MicroRNA as a Novel Modulator in Head and Neck Squamous Carcinoma
por: Chen, Li-Hsin, et al.
Publicado: (2010)

MicroRNAs and cell proliferation in head and neck squamous cell carcinoma
por: Andreghetto, Flavia M, et al.
Publicado: (2013)

Pretreatment dietary intake is associated with tumor suppressor DNA methylation in head and neck squamous cell carcinomas
por: Colacino, Justin A., et al.
Publicado: (2012)

The Role of MicroRNAs in Recurrence and Metastasis of Head and Neck Squamous Cell Carcinoma
por: Yang, Chris X., et al.
Publicado: (2019)

Rh type C-glycoprotein functions as a novel tumor suppressor gene by inhibiting tumorigenicity and metastasis in head and neck squamous cell carcinoma
por: Xu, Wenguang, et al.
Publicado: (2019)

MicroRNAs in Head and Neck Squamous Cell Carcinoma (HNSCC) and Oral Squamous Cell Carcinoma (OSCC)
por: Shiiba, Masashi, et al.
Publicado: (2010)

Single-cell transcriptome analysis reveals the clinical implications of myeloid-derived suppressor cells in head and neck squamous cell carcinoma
por: Jiang, Wenru, et al.
Publicado: (2023)

microRNA-107 functions as a candidate tumor suppressor gene in head and neck squamous cell carcinoma by down-regulation of protein kinase Cε
por: Datta, Jharna, et al.
Publicado: (2011)

The Tumour Suppressor CYLD Is Required for Clathrin-Mediated Endocytosis of EGFR and Cetuximab-Induced Apoptosis in Head and Neck Squamous Cell Carcinoma
por: Liu, Rin, et al.
Publicado: (2021)

CCTs as new biomarkers for the prognosis of head and neck squamous cancer
por: Dong, Yanbo, et al.
Publicado: (2020)

MicroRNA-21 induces cisplatin resistance in head and neck squamous cell carcinoma
por: Sheng, Shuyan, et al.
Publicado: (2022)

Network Modeling Identifies Molecular Functions Targeted by miR-204 to Suppress Head and Neck Tumor Metastasis
por: Lee, Younghee, et al.
Publicado: (2010)

The methylation modification of m6A regulators contributes to the prognosis of head and neck squamous cell carcinoma
por: Chen, Ying, et al.
Publicado: (2021)

A Novel Tumor Suppressor SPINK5 Serves as an Independent Prognostic Predictor for Patients with Head and Neck Squamous Cell Carcinoma
por: Lv, Zhongjing, et al.
Publicado: (2020)

MicroRNA-204-5p inhibits invasion and metastasis of laryngeal squamous cell carcinoma by suppressing forkhead box C1
por: Gao, Wei, et al.
Publicado: (2017)

LncRNAs as an intermediate in HPV16 promoting myeloid-derived suppressor cell recruitment of head and neck squamous cell carcinoma
por: Ma, Xiangrui, et al.
Publicado: (2017)

Promoter methylation of MGMT, MLH1 and RASSF1A tumor suppressor genes in head and neck squamous cell carcinoma: Pharmacological genome demethylation reduces proliferation of head and neck squamous carcinoma cells
por: KOUTSIMPELAS, DIMITRIOS, et al.
Publicado: (2012)

Changes in Protein Glycosylation in Head and Neck Squamous Cell Carcinoma
por: Liao, Chengcheng, et al.
Publicado: (2021)

Synthetic Evaluation of MicroRNA-1-3p Expression in Head and Neck Squamous Cell Carcinoma Based on Microarray Chips and MicroRNA Sequencing
por: Chen, Yubing, et al.
Publicado: (2021)

The prognostic value of MicroRNAs associated with fatty acid metabolism in head and neck squamous cell carcinoma
por: Wang, Xiaojing, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_5f4pn0av46et5mm3v9fn8242k8