Specific targeting of PDGFRβ in the stroma inhibits growth and angiogenesis in tumors with high PDGF-BB expression

PDGF-BB/PDGFRβ signaling plays an important role during vascularization by mediating pericyte recruitment to the vasculature, promoting the integrity and function of vessels. Until now it has not been possible to assess the specific role of PDGFRβ signaling in tumor progression and angiogenesis due...

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Detalles Bibliográficos
Autores principales: Tsioumpekou, Maria, Cunha, Sara I., Ma, Haisha, Åhgren, Aive, Cedervall, Jessica, Olsson, Anna-Karin, Heldin, Carl-Henrik, Lennartsson, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956815/
https://www.ncbi.nlm.nih.gov/pubmed/31938055
http://dx.doi.org/10.7150/thno.37851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956815/
https://www.ncbi.nlm.nih.gov/pubmed/31938055
http://dx.doi.org/10.7150/thno.37851

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