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Management of delirium at an academic medical center: Plans for antipsychotic prescribing upon discharge

INTRODUCTION: Delirium is an acute, fluctuating change in mental status, often associated with behavioral manifestations such as agitation. Literature suggests that many patients who continue on antipsychotics for extended management of delirium are not provided instructions for discontinuation. How...

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Autores principales: Halavonich, Lauren, Robert, Sophie, McGraw, Dan, Weeda, Erin, Mullinax, Kristen, Bass, Bailey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: College of Psychiatric & Neurologic Pharmacists 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956973/
https://www.ncbi.nlm.nih.gov/pubmed/31942275
http://dx.doi.org/10.9740/mhc.2020.01.025
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author Halavonich, Lauren
Robert, Sophie
McGraw, Dan
Weeda, Erin
Mullinax, Kristen
Bass, Bailey
author_facet Halavonich, Lauren
Robert, Sophie
McGraw, Dan
Weeda, Erin
Mullinax, Kristen
Bass, Bailey
author_sort Halavonich, Lauren
collection PubMed
description INTRODUCTION: Delirium is an acute, fluctuating change in mental status, often associated with behavioral manifestations such as agitation. Literature suggests that many patients who continue on antipsychotics for extended management of delirium are not provided instructions for discontinuation. However, there is a positive correlation between consult services and instructions for discontinuation. The objective of this study was to determine the frequency at which patients with delirium were prescribed an antipsychotic at hospital discharge and to characterize discharge antipsychotic prescribing for psychiatric consult and nonconsult cohorts. METHODS: This study was a retrospective chart review of adult patients with an International Classification of Diseases 10th revision code of delirium who received at least 1 dose of antipsychotic during their admission. Inclusion criteria were all patients aged 18 years or older with a diagnosis of or relating to delirium who were administered antipsychotics during their admission. RESULTS: A total of 152 patients were included, of which 43 received a psychiatric consult. Antipsychotics were prescribed at discharge for management of delirium for 52 (34.2%) of 152 total patients. More patients in the psychiatric consult cohort were discharged with an antipsychotic as compared to those in the nonconsult cohort (53.3% vs 26.6%, P =  .02). DISCUSSION: Compared to previous studies, patients in this retrospective review were more likely to be discharged on an antipsychotic that was initiated during admission for management of delirium. Findings from this study also align with prior research demonstrating a positive association between antipsychotic discharge instructions and specialty consult recommendations.
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spelling pubmed-69569732020-01-15 Management of delirium at an academic medical center: Plans for antipsychotic prescribing upon discharge Halavonich, Lauren Robert, Sophie McGraw, Dan Weeda, Erin Mullinax, Kristen Bass, Bailey Ment Health Clin Original Research INTRODUCTION: Delirium is an acute, fluctuating change in mental status, often associated with behavioral manifestations such as agitation. Literature suggests that many patients who continue on antipsychotics for extended management of delirium are not provided instructions for discontinuation. However, there is a positive correlation between consult services and instructions for discontinuation. The objective of this study was to determine the frequency at which patients with delirium were prescribed an antipsychotic at hospital discharge and to characterize discharge antipsychotic prescribing for psychiatric consult and nonconsult cohorts. METHODS: This study was a retrospective chart review of adult patients with an International Classification of Diseases 10th revision code of delirium who received at least 1 dose of antipsychotic during their admission. Inclusion criteria were all patients aged 18 years or older with a diagnosis of or relating to delirium who were administered antipsychotics during their admission. RESULTS: A total of 152 patients were included, of which 43 received a psychiatric consult. Antipsychotics were prescribed at discharge for management of delirium for 52 (34.2%) of 152 total patients. More patients in the psychiatric consult cohort were discharged with an antipsychotic as compared to those in the nonconsult cohort (53.3% vs 26.6%, P =  .02). DISCUSSION: Compared to previous studies, patients in this retrospective review were more likely to be discharged on an antipsychotic that was initiated during admission for management of delirium. Findings from this study also align with prior research demonstrating a positive association between antipsychotic discharge instructions and specialty consult recommendations. College of Psychiatric & Neurologic Pharmacists 2020-01-09 /pmc/articles/PMC6956973/ /pubmed/31942275 http://dx.doi.org/10.9740/mhc.2020.01.025 Text en © 2020 CPNP. The Mental Health Clinician is a publication of the College of Psychiatric and Neurologic Pharmacists. http://creativecommons.org/licenses/by-nc/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License, which permits non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Research
Halavonich, Lauren
Robert, Sophie
McGraw, Dan
Weeda, Erin
Mullinax, Kristen
Bass, Bailey
Management of delirium at an academic medical center: Plans for antipsychotic prescribing upon discharge
title Management of delirium at an academic medical center: Plans for antipsychotic prescribing upon discharge
title_full Management of delirium at an academic medical center: Plans for antipsychotic prescribing upon discharge
title_fullStr Management of delirium at an academic medical center: Plans for antipsychotic prescribing upon discharge
title_full_unstemmed Management of delirium at an academic medical center: Plans for antipsychotic prescribing upon discharge
title_short Management of delirium at an academic medical center: Plans for antipsychotic prescribing upon discharge
title_sort management of delirium at an academic medical center: plans for antipsychotic prescribing upon discharge
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956973/
https://www.ncbi.nlm.nih.gov/pubmed/31942275
http://dx.doi.org/10.9740/mhc.2020.01.025
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