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The role of survivin in the progression of pancreatic ductal adenocarcinoma (PDAC) and a novel survivin-targeted therapeutic for PDAC
Treating pancreatic ductal adenocarcinoma (PDAC) remains a major hurdle in the field of oncology. Less than half of patients respond to frontline chemotherapy and the pancreatic tumor microenvironment limits the efficacy of immunotherapeutic approaches. Targeted therapies could serve as effective tr...
Autores principales: | Brown, Matthew, Zhang, Wanbin, Yan, Deyue, Kenath, Rajath, Le, Le, Wang, He, Delitto, Daniel, Ostrov, David, Robertson, Keith, Liu, Chen, Pham, Kien |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957139/ https://www.ncbi.nlm.nih.gov/pubmed/31929540 http://dx.doi.org/10.1371/journal.pone.0226917 |
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