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Functional analysis of Rossmann-like domains reveals convergent evolution of topology and reaction pathways

Rossmann folds are ancient, frequently diverged domains found in many biological reaction pathways where they have adapted for different functions. Consequently, discernment and classification of their homologous relations and function can be complicated. We define a minimal Rossmann-like structure...

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Detalles Bibliográficos
Autores principales: Medvedev, Kirill E., Kinch, Lisa N., Schaeffer, R. Dustin, Grishin, Nick V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957218/
https://www.ncbi.nlm.nih.gov/pubmed/31869345
http://dx.doi.org/10.1371/journal.pcbi.1007569