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High level MYC amplification in B-cell lymphomas: is it a marker of aggressive disease?

While MYC translocations in B-cell lymphoma (BCL) have been extensively studied, the significance of MYC amplification (MYC amp) is poorly understood. This study characterizes BCL showing MYC amp, defined as uncountable FISH signals. Retrospective analysis of all BCL FISH for MYC aberrations perform...

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Detalles Bibliográficos
Autores principales:	Pophali, Priyanka A., Marinelli, Lisa M., Ketterling, Rhett P., Meyer, Reid G., McPhail, Ellen D., Kurtin, Paul J., Mwangi, Raphael, Maurer, Matthew J., Habermann, Thomas, King, Rebecca L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957498/ https://www.ncbi.nlm.nih.gov/pubmed/31932576 http://dx.doi.org/10.1038/s41408-019-0271-z

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