Cargando…
SIK2 enhances synthesis of fatty acid and cholesterol in ovarian cancer cells and tumor growth through PI3K/Akt signaling pathway
Salt-inducible kinase 2 (SIK2) has been established as a regulator of diverse biological processes including cell metabolism. A recent study has reported that SIK2 is required for adipocyte-induced ovarian cancer (OC) survival through facilitating fatty acid oxidation. However, whether SIK2 also pla...
Autores principales: | Zhao, Jing, Zhang, Xiaohong, Gao, Tian, Wang, Shanci, Hou, Yiran, Yuan, Peng, Yang, Yi, Yang, Tao, Xing, Jinliang, Li, Jibin, Liu, Shujuan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957524/ https://www.ncbi.nlm.nih.gov/pubmed/31932581 http://dx.doi.org/10.1038/s41419-019-2221-x |
Ejemplares similares
-
SIK2 attenuates proliferation and survival of breast cancer cells with simultaneous perturbation of MAPK and PI3K/Akt pathways
por: Zohrap, Neslihan, et al.
Publicado: (2018) -
Increased mitochondrial fission drives the reprogramming of fatty acid metabolism in hepatocellular carcinoma cells through suppression of Sirtuin 1
por: Wu, Dan, et al.
Publicado: (2022) -
Loss of the conserved PKA sites of SIK1 and SIK2 increases sleep need
por: Park, Minjeong, et al.
Publicado: (2020) -
Inhibition of SIK2 and SIK3 during differentiation enhances the anti-inflammatory phenotype of macrophages
por: Darling, Nicola J., et al.
Publicado: (2017) -
SIK2 promotes ovarian cancer cell motility and metastasis by phosphorylating MYLK
por: Shi, Xiu, et al.
Publicado: (2022)