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In Vivo Validation of a Small Molecule Inhibitor of Tau Self-Association in htau Mice

Tau oligomers have been shown to transmit tau pathology from diseased neurons to healthy neurons through seeding, tau misfolding, and aggregation that is thought to play an influential role in the progression of Alzheimer’s disease (AD) and related tauopathies. To develop a small molecule therapeuti...

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Detalles Bibliográficos
Autores principales:	Davidowitz, Eliot J., Krishnamurthy, Pavan K., Lopez, Patricia, Jimenez, Heidy, Adrien, Leslie, Davies, Peter, Moe, James G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957711/ https://www.ncbi.nlm.nih.gov/pubmed/31771053 http://dx.doi.org/10.3233/JAD-190465

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