Cargando…

Methylglyoxal interaction with superoxide dismutase 1

Methylglyoxal (MG) is a highly reactive aldehyde spontaneously formed in human cells mainly as a by-product of glycolysis. Such endogenous metabolite reacts with proteins, nucleotides and lipids forming advanced glycation end-products (AGEs). MG binds to arginine, lysine and cysteine residues of pro...

Descripción completa

Detalles Bibliográficos
Autores principales: Polykretis, Panagis, Luchinat, Enrico, Boscaro, Francesca, Banci, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957824/
https://www.ncbi.nlm.nih.gov/pubmed/31931282
http://dx.doi.org/10.1016/j.redox.2019.101421