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Methylglyoxal interaction with superoxide dismutase 1
Methylglyoxal (MG) is a highly reactive aldehyde spontaneously formed in human cells mainly as a by-product of glycolysis. Such endogenous metabolite reacts with proteins, nucleotides and lipids forming advanced glycation end-products (AGEs). MG binds to arginine, lysine and cysteine residues of pro...
Autores principales: | Polykretis, Panagis, Luchinat, Enrico, Boscaro, Francesca, Banci, Lucia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957824/ https://www.ncbi.nlm.nih.gov/pubmed/31931282 http://dx.doi.org/10.1016/j.redox.2019.101421 |
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