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Improved Nucleic Acid Therapy with Advanced Nanoscale Biotechnology

Due to a series of systemic and intracellular obstacles in nucleic acid (NA) therapy, including fast degradation in blood, renal clearance, poor cellular uptake, and inefficient endosomal escape, NAs may need delivery methods to transport to the cell nucleus or cytosol to be effective. Advanced nano...

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Detalles Bibliográficos
Autores principales:	Weng, Yuhua, Huang, Qianqian, Li, Chunhui, Yang, Yongfeng, Wang, Xiaoxia, Yu, Jie, Huang, Yuanyu, Liang, Xing-Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957827/ https://www.ncbi.nlm.nih.gov/pubmed/31927331 http://dx.doi.org/10.1016/j.omtn.2019.12.004

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