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A deeper understanding of intestinal organoid metabolism revealed by combining fluorescence lifetime imaging microscopy (FLIM) and extracellular flux analyses

Stem cells and the niche in which they reside feature a complex microenvironment with tightly regulated homeostasis, cell-cell interactions and dynamic regulation of metabolism. A significant number of organoid models has been described over the last decade, yet few methodologies can enable single c...

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Detalles Bibliográficos
Autores principales:	Okkelman, Irina A., Neto, Nuno, Papkovsky, Dmitri B., Monaghan, Michael G., Dmitriev, Ruslan I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Method Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957829/ https://www.ncbi.nlm.nih.gov/pubmed/31935648 http://dx.doi.org/10.1016/j.redox.2019.101420

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