Novel Human NKCC1 Mutations Cause Defects in Goblet Cell Mucus Secretion and Chronic Inflammation

BACKGROUND & AIMS: Infections resulting from intestinal yeast and bacteria affect a large number of patients with deficits in absorptive or secretory epithelial transport mechanisms. The basolateral Na(+)-K(+)-2Cl(-) cotransporter (NKCC1) has been implicated in intestinal epithelial fluid secret...

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Detalles Bibliográficos
Autores principales: Koumangoye, Rainelli, Omer, Salma, Kabeer, Mustafa H., Delpire, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957845/
https://www.ncbi.nlm.nih.gov/pubmed/31655271
http://dx.doi.org/10.1016/j.jcmgh.2019.10.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957845/
https://www.ncbi.nlm.nih.gov/pubmed/31655271
http://dx.doi.org/10.1016/j.jcmgh.2019.10.006

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