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Intra-Articular Hyaluronic Acid and Chondroitin Sulfate: Pharmacokinetic Investigation in Osteoarthritic Rat Models

BACKGROUND: Viscosupplementation of synovial fluid with intra-articular (IA) injections of hyaluronic acid (HA) is widely used for symptomatic treatment of osteoarthritis (OA). Herein we present HCS, a new combination of chemicals, associating HA and chondroitin sulfate (CS), both members of the gly...

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Detalles Bibliográficos
Autores principales:	Fonsi, Massimiliano, El Amrani, Abdel-Ilah, Gervais, Frédéric, Vincent, Patrice
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957868/ https://www.ncbi.nlm.nih.gov/pubmed/31956378 http://dx.doi.org/10.1016/j.curtheres.2019.100573

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