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A Case History in Cooperative Biological Research: Compendium of Studies and Program Analyses in Kazakhstan

Kazakhstan and the United States have partnered since 2003 to counter the proliferation of weapons of mass destruction. The US Department of Defense (US DoD) has funded threat reduction programs to eliminate biological weapons, secure material in repositories that could be targeted for theft, and en...

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Autores principales: Yeh, Kenneth B., Parekh, Falgunee K., Musralina, Lyazzat, Sansyzbai, Ablay, Tabynov, Kairat, Shapieva, Zhanna, Richards, Allen L., Hay, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958332/
https://www.ncbi.nlm.nih.gov/pubmed/31717575
http://dx.doi.org/10.3390/tropicalmed4040136
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author Yeh, Kenneth B.
Parekh, Falgunee K.
Musralina, Lyazzat
Sansyzbai, Ablay
Tabynov, Kairat
Shapieva, Zhanna
Richards, Allen L.
Hay, John
author_facet Yeh, Kenneth B.
Parekh, Falgunee K.
Musralina, Lyazzat
Sansyzbai, Ablay
Tabynov, Kairat
Shapieva, Zhanna
Richards, Allen L.
Hay, John
author_sort Yeh, Kenneth B.
collection PubMed
description Kazakhstan and the United States have partnered since 2003 to counter the proliferation of weapons of mass destruction. The US Department of Defense (US DoD) has funded threat reduction programs to eliminate biological weapons, secure material in repositories that could be targeted for theft, and enhance surveillance systems to monitor infectious disease outbreaks that would affect national security. The cooperative biological research (CBR) program of the US DoD’s Biological Threat Reduction Program has provided financing, mentorship, infrastructure, and biologic research support to Kazakhstani scientists and research institutes since 2005. The objective of this paper is to provide a historical perspective for the CBR involvement in Kazakhstan, including project chronology, successes and challenges to allow lessons learned to be applied to future CBR endeavors. A project compendium from open source data and interviews with partner country Kazakhstani participants, project collaborators, and stakeholders was developed utilizing studies from 2004 to the present. An earlier project map was used as a basis to determine project linkages and continuations during the evolution of the CBR program. It was determined that consistent and effective networking increases the chances to collaborate especially for competitive funding opportunities. Overall, the CBR program has increased scientific capabilities in Kazakhstan while reducing their risk of biological threats. However, there is still need for increased scientific transparency and an overall strategy to develop a capability-based model to better enhance and sustain future research. Finally, we offer a living perspective that can be applied to further link related studies especially those related to One Health and zoonoses and the assessment of similar capability-building programs.
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spelling pubmed-69583322020-01-23 A Case History in Cooperative Biological Research: Compendium of Studies and Program Analyses in Kazakhstan Yeh, Kenneth B. Parekh, Falgunee K. Musralina, Lyazzat Sansyzbai, Ablay Tabynov, Kairat Shapieva, Zhanna Richards, Allen L. Hay, John Trop Med Infect Dis Review Kazakhstan and the United States have partnered since 2003 to counter the proliferation of weapons of mass destruction. The US Department of Defense (US DoD) has funded threat reduction programs to eliminate biological weapons, secure material in repositories that could be targeted for theft, and enhance surveillance systems to monitor infectious disease outbreaks that would affect national security. The cooperative biological research (CBR) program of the US DoD’s Biological Threat Reduction Program has provided financing, mentorship, infrastructure, and biologic research support to Kazakhstani scientists and research institutes since 2005. The objective of this paper is to provide a historical perspective for the CBR involvement in Kazakhstan, including project chronology, successes and challenges to allow lessons learned to be applied to future CBR endeavors. A project compendium from open source data and interviews with partner country Kazakhstani participants, project collaborators, and stakeholders was developed utilizing studies from 2004 to the present. An earlier project map was used as a basis to determine project linkages and continuations during the evolution of the CBR program. It was determined that consistent and effective networking increases the chances to collaborate especially for competitive funding opportunities. Overall, the CBR program has increased scientific capabilities in Kazakhstan while reducing their risk of biological threats. However, there is still need for increased scientific transparency and an overall strategy to develop a capability-based model to better enhance and sustain future research. Finally, we offer a living perspective that can be applied to further link related studies especially those related to One Health and zoonoses and the assessment of similar capability-building programs. MDPI 2019-11-09 /pmc/articles/PMC6958332/ /pubmed/31717575 http://dx.doi.org/10.3390/tropicalmed4040136 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Yeh, Kenneth B.
Parekh, Falgunee K.
Musralina, Lyazzat
Sansyzbai, Ablay
Tabynov, Kairat
Shapieva, Zhanna
Richards, Allen L.
Hay, John
A Case History in Cooperative Biological Research: Compendium of Studies and Program Analyses in Kazakhstan
title A Case History in Cooperative Biological Research: Compendium of Studies and Program Analyses in Kazakhstan
title_full A Case History in Cooperative Biological Research: Compendium of Studies and Program Analyses in Kazakhstan
title_fullStr A Case History in Cooperative Biological Research: Compendium of Studies and Program Analyses in Kazakhstan
title_full_unstemmed A Case History in Cooperative Biological Research: Compendium of Studies and Program Analyses in Kazakhstan
title_short A Case History in Cooperative Biological Research: Compendium of Studies and Program Analyses in Kazakhstan
title_sort case history in cooperative biological research: compendium of studies and program analyses in kazakhstan
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958332/
https://www.ncbi.nlm.nih.gov/pubmed/31717575
http://dx.doi.org/10.3390/tropicalmed4040136
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