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Innovating the Concept and Practice of Two-Dimensional Gel Electrophoresis in the Analysis of Proteomes at the Proteoform Level

Two-dimensional gel electrophoresis (2DE) is an important and well-established technical platform enabling extensive top-down proteomic analysis. However, the long-held but now largely outdated conventional concepts of 2DE have clearly impacted its application to in-depth investigations of proteomes...

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Detalles Bibliográficos
Autores principales: Zhan, Xianquan, Li, Biao, Zhan, Xiaohan, Schlüter, Hartmut, Jungblut, Peter R., Coorssen, Jens R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958347/
https://www.ncbi.nlm.nih.gov/pubmed/31671630
http://dx.doi.org/10.3390/proteomes7040036