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Unbiased Thiol-Labeling and Top-Down Proteomic Analyses Implicate Multiple Proteins in the Late Steps of Regulated Secretion
Regulated exocytosis enables temporal and spatial control over the secretion of biologically active compounds; however, the mechanism by which Ca(2+) modulates different stages of exocytosis is still poorly understood. For an unbiased, top-down proteomic approach, select thiol- reactive reagents wer...
Autores principales: | Furber, Kendra L., Backlund, Peter S., Yergey, Alfred L., Coorssen, Jens R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958363/ https://www.ncbi.nlm.nih.gov/pubmed/31569819 http://dx.doi.org/10.3390/proteomes7040034 |
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