A Decade of Antifungal Leads from Natural Products: 2010–2019

In this review, we discuss novel natural products discovered within the last decade that are reported to have antifungal activity against pathogenic species. Nearly a hundred natural products were identified that originate from bacteria, algae, fungi, sponges, and plants. Fungi were the most prolifi...

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Detalles Bibliográficos
Autores principales: Aldholmi, Mohammed, Marchand, Pascal, Ourliac-Garnier, Isabelle, Le Pape, Patrice, Ganesan, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958371/
https://www.ncbi.nlm.nih.gov/pubmed/31842280
http://dx.doi.org/10.3390/ph12040182
Descripción
Sumario:In this review, we discuss novel natural products discovered within the last decade that are reported to have antifungal activity against pathogenic species. Nearly a hundred natural products were identified that originate from bacteria, algae, fungi, sponges, and plants. Fungi were the most prolific source of antifungal compounds discovered during the period of review. The structural diversity of these antifungal leads encompasses all the major classes of natural products including polyketides, shikimate metabolites, terpenoids, alkaloids, and peptides.

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